The Canadian 24-Hour Movement Guidelines for Children and Youth (age 5–17 yr) consolidate evidence-informed daily requirements for physical activity, sedentary behavior, and sleep into 1 comprehensive resource. The primary objective of this study was to explore how parents of children and youth with disabilities (CYWD) perceive the guidelines. The secondary objective was to explore whether parents consider the guideline branding to be inclusive. A total of 15 mothers of CYWD participated in one 60-min semistructured interview, either in person or by telephone. The diffusion-of-innovation theory provided a theoretical basis for the interview guide. Mothers’ perspectives of the guidelines and branding are represented as seven themes. The results indicate that the guidelines and the branding are not inclusive or compatible with the abilities and needs of CYWD. Findings from this study provide a foundation for ongoing knowledge-translation activities aiming to address these limitations. Further revisions are necessary to promote full inclusion and uptake of the guidelines among CYWD.