Prolonged stress, poor coping skills, and a lack of engagement in self-care activities can contribute to burnout. We investigated perceived stress, burnout, and coping in Irish athletic therapy students. Moderate stress (20.5 ± 6.7), personal (57.5 ± 20.4), and work-related burnout (52.7 ± 18.1), along with low resilient coping (13.7 ± 2.4), overall (46.0 ± 15.6) and client-related (26.7 ± 17.2) burnout were noted. Women athletic therapy students presented with higher overall (r = .17, p = .04), personal (r = .20, p = .02), and work-related (r = .17, p = .03) burnout and lower resilient coping (r = .20, p = .02). Students working longer hours in employment had higher work- (r = .19, p = .04) and client-related (r = .19, p = .04) burnout scores. Thus, interventions to alleviate stress and burnout and enhance coping skills in students embarking on their career are urgently needed. Targeted strategies for women and those working a high number of hours in external employment are particularly required.