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To examine the effect of a nutritional supplement (ATP-E™) on high intensity exercise performance, 23 physically active males volunteered to perform six Wingate Anaerobic Power tests. Tests were performed prior to and at 14 and 21 days during ATP-E~o~r placebo ingestion. f i e experiment followed a double-blind and random-order design. Twelve subjects (responders, R) showed an increase in preexercise blood ATP on Day 14 of ATP-E™ ingestion compared to control measures. The remaining 11 subjects (nonresponders, NR) had no change in pree~e~cibselo od ATP. Peak power and mean power were unchanged for both R and NR subjects across the exercise tests, but R experienced a decrease (p < 0.05) in immediate postexercise plasma lactate on Day 14 of ATP-E™ testing compared to their control measures. NR had no change in peak plasma lactate at any time during the study. The results suggest that short-term high intensity exercise performance was maintained in R with less reliance on anaerobic metabolism, and that response was evident following 14 days of ATP-E™ ingestion.

The authors are with the Dept. of Sport, Leisure, and Exercise Sciences and the Dept. of Physiology and Neurobiology at the Univ. of Connecticut. Request reprints from Carl M. Maresh, Human Performance Laboratory, Sports Center, U-110, the University of Connecticut, Storrs, CT 06269-1110.