Effect of Creatine and ß-Alanine Supplementation on Performance and Endocrine Responses in Strength/Power Athletes

in International Journal of Sport Nutrition and Exercise Metabolism

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Jay Hoffman
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Nicholas Ratamess
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Jie Kang
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Gerald Mangine
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Avery Faigenbaum
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Jeffrey Stout
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The effects of creatine and creatine plus β-alanine on strength, power, body composition, and endocrine changes were examined during a 10-wk resistance training program in collegiate football players. Thirty-three male subjects were randomly assigned to either a placebo (P), creatine (C), or creatine plus β-alanine (CA) group. During each testing session subjects were assessed for strength (maximum bench press and squat), power (Wingate anaerobic power test, 20-jump test), and body composition. Resting blood samples were analyzed for total testosterone, cortisol, growth hormone, IGF-1, and sex hormone binding globulin. Changes in lean body mass and percent body fat were greater (P < 0.05) in CA compared to C or P. Significantly greater strength improvements were seen in CA and C compared to P. Resting testosterone concentrations were elevated in C, however, no other significant endocrine changes were noted. Results of this study demonstrate the efficacy of creatine and creatine plus β-alanine on strength performance. Creatine plus β-alanine supplementation appeared to have the greatest effect on lean tissue accruement and body fat composition.

Hoffman, Ratamess, Kang, Mangine, and Faigenbaum are with the Dept of Health and Exercise Science, The College of New Jersey, Ewing, NJ 08628. Stout is with the Dept of Health and Exercise Science, University of Oklahoma, Norman, OK 73019-6081.

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