The Effect of Probiotics on Respiratory Infections and Gastrointestinal Symptoms during Training in Marathon Runners

Click name to view affiliation

Riina A. Kekkonen
Search for other papers by Riina A. Kekkonen in
Current site
Google Scholar
PubMed
Close
,
Tommi J. Vasankari
Search for other papers by Tommi J. Vasankari in
Current site
Google Scholar
PubMed
Close
,
Timo Vuorimaa
Search for other papers by Timo Vuorimaa in
Current site
Google Scholar
PubMed
Close
,
Tari Haahtela
Search for other papers by Tari Haahtela in
Current site
Google Scholar
PubMed
Close
,
Ilkka Julkunen
Search for other papers by Ilkka Julkunen in
Current site
Google Scholar
PubMed
Close
, and
Riitta Korpela
Search for other papers by Riitta Korpela in
Current site
Google Scholar
PubMed
Close
Restricted access

Heavy exercise is associated with an increased risk of upper respiratory tract infections. Strenuous exercise also causes gastrointestinal (GI) symptoms. In previous studies probiotics have reduced respiratory tract infections and GI symptoms in general populations including children, adults, and the elderly. These questions have not been studied in athletes before. The purpose of this study was to investigate the effect of probiotics on the number of healthy days, respiratory infections, and GI-symptom episodes in marathon runners in the summer. Marathon runners (N = 141) were recruited for a randomized, double-blind intervention study during which they received Lactobacillus rhamnosus GG (LGG) or placebo for a 3-mo training period. At the end of the training period the subjects took part in a marathon race, after which they were followed up for 2 wk. The mean number of healthy days was 79.0 in the LGG group and 73.4 in the placebo group (P = 0.82). There were no differences in the number of respiratory infections or GI-symptom episodes. The duration of GI-symptom episodes in the LGG group was 2.9 vs. 4.3 d in the placebo group during the training period (P = 0.35) and 1.0 vs. 2.3 d, respectively, during the 2 wk after the marathon (P = 0.046). LGG had no effect on the incidence of respiratory infections or GI-symptom episodes in marathon runners, but it seemed to shorten the duration of GI-symptom episodes.

Kekkonen and Korpela are with the Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland 00370. Vasankari is with the Dept. of Health and Exercise, University of Turku, Turku, Finland. Vuorimaa is with the Sports Institute of Finland, Vierumäki, Finland. Haahtela is with Helsinki University Hospital, Skin and Allergy Hospital, Helsinki, Finland. Julkunen is with the Dept. of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland.

  • Collapse
  • Expand