A Simple Method for Increasing Levels of High-Density Lipoprotein Cholesterol: A Pilot Study of Combination Aerobic- and Resistance-Exercise Training

in International Journal of Sport Nutrition and Exercise Metabolism
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Evidence suggests that physical activity has a beneficial effect of elevated high-density lipoprotein cholesterol (HDL-C) on reducing coronary artery risk. However, previous studies show contrasting results for this association between different types of exercise training (i.e., aerobic, resistance, or combined aerobic and resistance training). The aim of this study was to determine which type of exercise training is more effective in increasing HDL-C levels. Forty obese men, age 18–29 yr, were randomized into 4 groups: an aerobic-training group (n = 10), a resistance-training group (n = 10), a combined-exercise-training group (n = 10), and a control group (n = 10). After a 12-wk exercise program, anthropometrics, blood biochemical variables, and physical-fitness components were compared with the data obtained at the baseline. Multiple-regression analysis was used to evaluate the association between different types of exercise training and changes in HDL-C while adjusting for potential confounders. The results showed that with the control group as the comparator, the effects of combined-exercise training (β = 4.17, p < .0001), aerobic training (β = 3.65, p < .0001), and resistance training (β = 2.10, p = .0001) were positively associated with increase in HDL-C after adjusting for potential confounders. Our findings suggested that a short-term exercise program can play an important role in increasing HDL-C levels; either aerobic or resistance training alone significantly increases the HDL-C levels, but the improvements are greatest with combined aerobic and resistance training.

Tseng is with the Office of Physical Education, Chung Hua University, Hsinchu City, Taiwan. Ho is with the Dept. of Health and Leisure Management, Yuanpei University, Hsinchu City, Taiwan. Chen is with the Dept. of Leisure Industry and Health Promotion, National Ilan University, Yilan County, Taiwan. Huang is with the School of Nutrition, and Liaw, the Dept. of Public Health and Inst. of Public Health, Chung Shan Medical University, Taichung City, Taiwan. Lai is with the Dept. and Graduate Inst. of Physical Education and Health, Taipei Physical Education College, Taipei City, Taiwan.