Effect of Conjugated Linoleic Acid Associated With Aerobic Exercise on Body Fat and Lipid Profile in Obese Women: A Randomized, Double-Blinded, and Placebo-Controlled Trial

in International Journal of Sport Nutrition and Exercise Metabolism
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The aim of this study was to analyze the effects of 8 weeks of conjugated linoleic acid (CLA) supplementation associated with aerobic exercise on body fat and lipid profile on obese women. We performed a randomized, double-blinded and placebo-controlled trial with 28 obese women who received 3.2 g/day of CLA or 4 g/day of olive oil (placebo group) while performing an 8-week protocol of aerobic exercise. Dietary intake (food record), body fat (dual-energy X-ray absorptiometry), and biochemical analysis (blood sample) were assessed before and after the intervention period. Independent of CLA supplementation, both groups improved (p < .05) oxygen uptake (CLA group, 13.2%; PLC group, 14.8%), trunk fat (CLA group, −1.0%; PLC group, −0.5%), leg fat (CLA group, −1.0%; PLC group, −1.6%), and total body fat (CLA group, −1.7%; PLC group, −1.3%) after the 8-week intervention. No main effect or Group × Time interaction was found for total cholesterol, triglycerides, and plasma lipoproteins (p > .05). We conclude that CLA supplementation associated with aerobic exercise has no effect on body fat reduction and lipid profile improvements over placebo in young adult obese women.

Ribeiro, Pina, Silva, Sugihara Júnior, Fernandes, and Cyrino are with the Physical Education and Sport Center, Londrina State University, Londrina, Brazil. Schoenfeld is with the Exercise Science Department, CUNY Lehman College, Bronx, New York, USA. Dodero is with the Palmas Lutheran University Centre, Palmas, Brazil. Barbosa is with Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, Londrina State University, Londrina, Brazil. Tirapegui is with the Food and Experimental Nutrition Department, University of São Paulo, São Paulo, Brazil.

Address author correspondence to Alex S. Ribeiro at alex-silvaribeiro@hotmail.com.