The Effect of 1 Week of a Multi-ingredient Dietary Preworkout Supplement on Resting and Postacute Resistance Exercise Vascular Function

in International Journal of Sport Nutrition and Exercise Metabolism
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  • 1 University of Delaware
  • 2 University of Illinois at Chicago
  • 3 Federal University of São Carlos
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Dietary preworkout supplements are popular among recreational exercisers and athletes. However, the effects of these supplements on the vasculature, both at rest and during exercise, are not well studied. Therefore, the purpose of this study was to determine the effect of 1 week of supplementation with a multi-ingredient dietary preworkout supplement on measures of vascular function at rest and immediately following acute resistance exercise in young, recreationally active adults. Twelve participants (9 males and 3 females; mean ± SD: age = 24.5 ± 3.4 years and body mass index = 24.3 ± 4.7 kg/m2) completed this double-blind, randomized, crossover design study. After familiarization, participants were randomized to either a taste-matched placebo or the preworkout supplement for 1 week preceding the testing visits. Participants underwent measures of vascular function, including brachial artery flow-mediated dilation, measures of central and peripheral blood pressure, and measures of arterial stiffness via pulse wave analysis and pulse wave velocity. All measures were taken at rest and immediately following an acute bilateral leg press exercise session. Resting and postacute exercise flow-mediated dilation, blood pressure, and arterial stiffness were similar between the placebo and the preworkout supplement visits. One week of multi-ingredient preworkout supplementation does not affect vascular function at rest or in response to an acute bout of resistance exercise in young, healthy, recreationally active individuals.

Robinson is with the Dept. of Kinesiology & Applied Physiology, University of Delaware, Newark, DE. Robinson, Mazzuco, Sabbahi, and Phillips are with the Dept. of Physical Therapy, University of Illinois at Chicago, Chicago, IL. Robinson, Sabbahi, and Phillips are also with Integrative Physiology Laboratory, University of Illinois at Chicago, Chicago, IL. Mazzuco and Borghi-Silva are with Cardiopulmonary Physiotherapy Laboratory, Federal University of São Carlos, São Carlos, Brazil.

Address author correspondence to Shane A. Phillips at shanep@uic.edu.
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