Combining Plant Sterols With Walking Lowers Postprandial Triacylglycerol More Than Walking Only in Chinese Men With Elevated Body Mass Index

in International Journal of Sport Nutrition and Exercise Metabolism
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This study examined if plant sterols and walking reduce postprandial triacylglycerol (TAG) concentrations in Chinese men with elevated body mass index (≥ 23.5 kg/m2). Fifteen Chinese men (mean [SD]: age = 25 [3] years and body mass index = 26.2 [1.5] kg/m2] completed four 10-day trials in random order with a 7- to 10-day washout between trials: (a) daily consumption of a control margarine while sedentary (C-S), (b) daily consumption of margarine containing 2 g/day of plant sterols while sedentary (PS-S), (c) daily consumption of a control margarine with 30-min daily walking (C-W), and (d) daily consumption of margarine containing 2 g/day of plant sterols with 30-min daily walking (PS-W). On Day 11 of each trial, postprandial TAG was measured after a high-fat milkshake. The 5-hr total area under the TAG curve was 22%, 25%, and 12% lower on PS-W (mean [SD]: 8.9 [4.3] mmol·5 hr/L) than C-S (11.4 [4.5] mmol·5 hr/L; p = .005; d = 0.56), PS-S (11.9 [4.9] mmol·5 hr/L; p = .004; d = 0.67), and C-W (10.1 [4.4] mmol·5 hr/L; p = .044; d = 0.27) trials, respectively. Similarly, 5-hr incremental area for PS-W (4.5 [2.7] mmol·5 hr/L) was 31%, 32%, and 18% lower than C-S (6.6 [3.3] mmol·5 hr/L; p = .005; d = 0.62), PS-S (6.6 [3.4] mmol·5 hr/L; p = .004; d = 0.64), and C-W (5.5 [2.8] mmol·5 hr/L; p = .032; d = 0.29). Ten days of daily plant sterol intake combined with walking presents an intervention strategy to lower postprandial TAG in Chinese men with elevated body mass index.

The authors are with Physical Education and Sports Science Academic Group, National Institute of Education, Nanyang Technological University, Singapore, Singapore.

Burns (stephen.burns@nie.edu.sg) is corresponding author.
  • Arjunan, S.P., Bishop, N.C., Reischak-Oliveira, A., & Stensel, D.J. (2013). Exercise and coronary heart disease risk markers in South Asian and European men. Medicine & Science in Sports & Exercise, 45(7), 1261–1268. PubMed ID: 23470315 doi:10.1249/MSS.0b013e3182853ecf

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Balke, B., & Ware, R.W. (1959). An experimental study of “physical fitness” of air force personnel. United States Armed Forces Medical Journal, 10(6), 675–688. PubMed ID: 13659732

    • Search Google Scholar
    • Export Citation
  • Baumgartner, S., Mensink, R.P., & Plat, J. (2016). Effects of a plant sterol or stanol enriched mixed meal on postprandial lipid metabolism in healthy subjects. PLoS ONE, 11(9), e0160396. PubMed ID: 27611192 doi:10.1371/journal.pone.0160396

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Borg, G.A. (1973). Perceived exertion: A note on history and methods. Medicine and Science in Sports, 5(2), 90–93. PubMed ID: 4721012

  • Catapano, A.L., Graham, I., De Backer, G., Wiklund, O., Chapman, M.J., Drexel, H., . . . Zamorano, J.L. (2016). 2016 ESC/EAS guidelines for the management of dyslipidaemias: The task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Atherosclerosis, 253, 281–344. PubMed ID: 27594540 doi:10.1016/j.atherosclerosis.2016.08.018

    • Search Google Scholar
    • Export Citation
  • Clifton, P.M., Mano, M., Duchateau, G.S., van der Knaap, H.C., & Trautwein, E.A. (2008). Dose-response effects of different plant sterol sources in fat spreads on serum lipids and C-reactive protein and on the kinetic behavior of serum plant sterols. European Journal of Clinical Nutrition, 62(8), 968–977. PubMed ID: 17538539 doi:10.1038/sj.ejcn.1602814

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Demonty, I., Chan, Y.M., Pelled, D., & Jones, P.J. (2006). Fish-oil esters of plant sterols improve the lipid profile of dyslipidemic subjects more than do fish-oil or sunflower oil esters of plant sterols. The American Journal of Clinical Nutrition, 84(6), 1534–1542. PubMed ID: 17158440 doi:10.1093/ajcn/84.6.1534

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Demonty, I., Ras, R.T., van der Knaap, H.C., Meijer, L., Zock, P.L., Geleijnse, J.M., & Trautwein, E.A. (2013). The effect of plant sterols on serum triglyceride concentrations is dependent on baseline concentrations: A pooled analysis of 12 randomised controlled trials. European Journal of Nutrition, 52(1), 153–160. PubMed ID: 22252793 doi:10.1007/s00394-011-0297-x

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Friedewald, W.T., Levy, R.I., & Fredrickson, D.S. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, 18(6), 499–502. PubMed ID: 4337382

    • Search Google Scholar
    • Export Citation
  • Ghafouri, K., Cooney, J., Bedford, D.K., Wilson, J., Caslake, M.J., & Gill, J.M. (2015). Moderate exercise increases affinity of large very low-density lipoproteins for hydrolysis by lipoprotein lipase. The Journal of Clinical Endocrinology & Metabolism, 100(6), 2205–2213. PubMed ID: 25867814 doi:10.1210/jc.2015-1196

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Gylling, H., Plat, J., Turley, S., Ginsberg, H.N., Ellegard, L., Jessup, W., . . . European Atherosclerosis Society Consensus Panel on Phytosterols. (2014). Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease. Atherosclerosis, 232(2), 346–360. PubMed ID: 24468148 doi:10.1016/j.atherosclerosis.2013.11.043

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Halkes, C.J., Castro Cabezas, M., van Wijk, J.P., & Erkelens, D.W. (2001). Gender differences in diurnal triglyceridemia in lean and overweight subjects. International Journal of Obesity and Related Metabolic Disorders, 25(12), 1767–1774. PubMed ID: 11781756 doi:10.1038/sj.ijo.0801831

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Herd, S.L., Hardman, A.E., Boobis, L.H., & Cairns, C.J. (1998). The effect of 13 weeks of running training followed by 9 d of detraining on postprandial Lipaemia. The British Journal of Nutrition, 80(1), 57–66. PubMed ID: 9797644 doi:10.1017/S0007114598001779

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kolovou, G.D., Mikhailidis, D.P., Kovar, J., Lairon, D., Nordestgaard, B.G., Ooi, T.C., . . . Panotopoulos, G. (2011). Assessment and clinical relevance of non-fasting and postprandial triglycerides: An expert panel statement. Current Vascular Pharmacology, 9(3), 258–270. PubMed ID: 21314632 doi:10.2174/157016111795495549

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kraus, W.E., Houmard, J.A., Duscha, B.D., Knetzger, K.J., Wharton, M.B., McCartney, J.S., . . . Slentz, C.A. (2002). Effects of the amount and intensity of exercise on plasma lipoproteins. The New England Journal of Medicine, 347(19), 1483–1492. PubMed ID: 12421890 doi:10.1056/NEJMoa020194

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Li, N.Y., Li, K., Qi, Z., Demonty, I., Gordon, M., Francis, L., . . . Neal, B.C. (2007). Plant sterol-enriched milk tea decreases blood cholesterol concentrations in Chinese adults: A randomised controlled trial. The British Journal of Nutrition, 98(5), 978–983. PubMed ID: 17617940 doi:10.1017/S0007114507754302

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Malkova, D., & Gill, J.M. (2006). Effects of exercise on postprandial lipoprotein metabolism. Future Lipidology, 1(6), 743–755. doi:10.2217/17460875.1.6.743

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Maraki, M.I., & Sidossis, L.S. (2013). The latest on the effect of prior exercise on postprandial lipaemia. Sports Medicine, 43, 463–481. PubMed ID: 23580393 doi:10.1007/s40279-013-0046-9

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Marinangeli, C.P., Varady, K.A., & Jones, P.J. (2006). Plant sterols combined with exercise for the treatment of hypercholesterolemia: Overview of independent and synergistic mechanisms of action. The Journal of Nutritional Biochemistry, 17(4), 217–224. PubMed ID: 16410048 doi:10.1016/j.jnutbio.2005.09.003

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Nordestgaard, B.G., Benn, M., Schnohr, P., & Tybjaerg-Hansen, A. (2007). Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. The Journal of the American Medical Association, 298(3), 299–308. PubMed ID: 17635890 doi:10.1001/jama.298.3.299

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Plat, J., & Mensink, R.P. (2009). Plant stanol esters lower serum triacylglycerol concentrations via a reduced hepatic VLDL-1 production. Lipids, 44(12), 1149–1153. PubMed ID: 19856194 doi:10.1007/s11745-009-3361-z

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Rideout, T.C., Harding, S.V., & Jones, P.J. (2010). Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. Molecular Nutrition & Food Research, 54(S1), S7–S13. doi:10.1002/mnfr.201000027

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Schonewille, M., Brufau, G., Shiri-Sverdlov, R., Groen, A.K., & Plat, J. (2014). Serum TG-lowering properties of plant sterols and stanols are associated with decreased hepatic VLDL secretion. Journal of Lipid Research, 55(12), 2554–2561. PubMed ID: 25348863 doi:10.1194/jlr.M052407

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Varady, K.A., Ebine, N., Vanstone, C.A., Parsons, W.E., & Jones, P.J. (2004). Plant sterols and endurance training combine to favorably alter plasma lipid profiles in previously sedentary hypercholesterolemic adults after 8 wk. The American Journal of Clinical Nutrition, 80(5), 1159–1166. PubMed ID: 15531661 doi:10.1093/ajcn/80.5.1159

    • Crossref
    • Search Google Scholar
    • Export Citation
  • WHO Expert Consultation. (2004). Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. The Lancet, 363(9403), 157–163. doi:10.1016/S0140-6736(03)15268-3

    • Search Google Scholar
    • Export Citation
  • Wing, R.R., Tate, D.F., Gorin, A.A., Raynor, H.A., & Fava, J.L. (2006). A self-regulation program for maintenance of weight loss. The New England Journal of Medicine, 355(15), 1563–1571. PubMed ID: 17035649 doi:10.1056/NEJMoa061883

    • Crossref
    • Search Google Scholar
    • Export Citation
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