The first sport-science-oriented and comprehensive paper on magnitude-based inferences (MBI) was published 10 y ago in the first issue of this journal. While debate continues, MBI is today well established in sport science and in other fields, particularly clinical medicine, where practical/clinical significance often takes priority over statistical significance. In this commentary, some reasons why both academics and sport scientists should abandon null-hypothesis significance testing and embrace MBI are reviewed. Apparent limitations and future areas of research are also discussed. The following arguments are presented: P values and, in turn, study conclusions are sample-size dependent, irrespective of the size of the effect; significance does not inform on magnitude of effects, yet magnitude is what matters the most; MBI allows authors to be honest with their sample size and better acknowledge trivial effects; the examination of magnitudes per se helps provide better research questions; MBI can be applied to assess changes in individuals; MBI improves data visualization; and MBI is supported by spreadsheets freely available on the Internet. Finally, recommendations to define the smallest important effect and improve the presentation of standardized effects are presented.