Purpose: To explore the acute effects of caffeinated chewing gum on vertical-jump performance, isokinetic knee-extension/flexion strength and power, barbell velocity in resistance exercise, and whole-body power. Methods: Nineteen resistance-trained men consumed, in randomized counterbalanced order, either caffeinated chewing gum (300 mg of caffeine) or placebo and completed exercise testing that included squat jump; countermovement jump; isokinetic knee extension and knee flexion at angular velocities of 60 and 180°·s−1; bench-press exercise with loads corresponding to 50%, 75%, and 90% of 1-repetition maximum (1RM); and an “all-out” rowing-ergometer test. Results: Compared with placebo, caffeinated chewing gum enhanced (all Ps < .05) (1) vertical-jump height in the squat jump (effect size [ES] = 0.21; +3.7%) and countermovement jump (ES = 0.27; +4.6%); (2) knee-extension peak torque (ES = 0.21; +3.6%) and average power (ES = 0.25; +4.5%) at 60°·s−1 and knee-extension average power (ES = 0.30; +5.2%) at 180°·s−1, and knee-flexion peak torque at 60°·s−1 (ES = 0.22; +4.1%) and 180°·s−1 (ES = 0.31; +5.9%); (3) barbell velocity at 50% of 1RM (ES = 0.30; +3.2%), 75% of 1RM (ES = 0.44; +5.7%), and 90% of 1RM (ES = 0.43; +9.1%); and (4) whole-body peak power on the rowing-ergometer test (ES = 0.41; +5.0%). Average power of the knee flexors did not change at either angular velocity with caffeine consumption. Conclusions: Caffeinated chewing gum with a dose of caffeine of 300 mg consumed 10 min preexercise may acutely enhance vertical-jump height, isokinetic strength and power of the lower-body musculature, barbell velocity in the bench-press exercise with moderate to high loads, and whole-body power.