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Intensive training periods may negatively influence immune function, but the immunological consequences of specific high-intensity-training (HIT) prescriptions are not well defined. Purpose: To explore whether 3 different HIT prescriptions influence multiple health-related biomarkers and whether biomarker responses to HIT were associated with upper-respiratory-illness (URI) risk. Methods: Twenty-five male cyclists and triathletes were randomized to 3 HIT groups and completed 12 HIT sessions over 4 wk. Peak oxygen consumption (
Hanstock and Govus are with Swedish Winter Sports Research Center, Inst for Health Sciences, Mid Sweden University, Östersund, Sweden. Stenqvist, Sylta, and Torstveit are with the Faculty of Health and Sport Science, Dept of Public Health, Sport and Nutrition, University of Agder, Kristiansand, Norway.