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Context: Exercise improves the commonly impaired physical fitness and cardiovascular health of transplant recipients. However, concerns remain about the safety of strenuous physical exercise in this population. Purpose: To describe the physiological effects of ultraendurance exercise in a renal transplant recipient. Methods: After a 25-week training program, a 31-year-old male with stage 3 chronic kidney disease who had undergone 2 kidney transplants participated in a 62-km (5600 m of positive altitude change) trail-running race. Blood and urine analyses were performed at baseline (24 h before the race), 4 days after the race, and at different time points up to 16 weeks postexercise. Results: The participant completed the race in 12 hours 18 minutes. No noticeable side effects were recorded during the whole study period, including the prerace training program. No major urine or blood alterations were observed after ultraendurance exercise, with glomerular filtration rate remaining steady during the study period. Conclusions: Ultraendurance exercise induced no adverse physiological effects in a well-trained young renal transplant recipient.
Hernández-Sánchez and Ruiz are with the PROFITH Research Group, Dept of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain. Hernández-Sánchez is also with the Performance and Sport Rehabilitation Laboratory, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo, Spain. Valenzuela is with the Faculty of Sport Sciences, European University of Madrid, and Research Inst of Hospital 12 de Octubre, Madrid, Spain. Morales and Lucia are with the Faculty of Sport Sciences, European University of Madrid, Madrid, Spain. Lucia is also with the Research Inst of Hospital 12 de Octubre, Madrid, Spain. Carrero is with the Dept of Medical Epidemiology and Biostatistics, Karolinska Inst, Stockholm, Sweden.