Purpose: The subjective Volodalen® score (V®score) and the objective duty factor metric can both assess global running patterns. The authors aimed to investigate the relation between running economy (RE) at endurance running speeds and the global running pattern quantified using both subjective and objective measures. Methods: RE and 3-dimensional whole-body kinematics were acquired by indirect calorimetry and an optoelectronic system, respectively, for 52 trained runners during treadmill runs at 10, 12, and 14 km/h. Results: Correlations between RE and V®score and RE and duty factor were negligible and nonsignificant across speeds tested (P ≥ .20), except for a low and significant correlation between RE and V®score at 10 km/h. Conclusions: These findings suggest there is no global running pattern more economic than another at endurance running speeds. Therefore, there is no advantage of choosing, favoring, or prescribing one specific global running pattern along a continuum based on V®score or duty factor metrics, and coaches should not try to modify the spontaneous running pattern of runners at endurance running speed to improve RE.