Purpose: This study analyzed the influence of 2 velocity-based training-load prescription strategies (general vs individual load–velocity equations) on the relationship between the magnitude of velocity loss (VL) and the percentage of repetitions completed in the bench-press exercise. Methods: Thirty-five subjects completed 6 sessions consisting of performing the maximum number of repetitions to failure against their 40%, 60%, and 80% of 1-repetition maximum (1RM) in the Smith machine bench-press exercise using generalized and individualized equations to adjust the training load. Results: A close relationship and acceptable error were observed between percentage of repetitions completed and the percentage of VL reached for the 3 loading magnitudes and the 2 load-prescription strategies studied (R2 from .83 to .94; standard error of the estimate from 7% to 10%). A simple main effect was observed for load and VL thresholds but not for load-prescription strategies. No significant interaction effects were revealed. The 40% and 60% 1RM showed equivalence on data sets and the most regular variation, whereas the 80% 1-repetition maximum load showed no equivalence and more irregular variation. Conclusion: These results suggest that VL is a useful variable to predict percentage of repetitions completed in the bench-press exercise, regardless of the strategy selected to adjust the relative load. However, caution should be taken when using heavy loads.