Caffeine Does Not Augment Markers of Muscle Damage or Leukocytosis Following Resistance Exercise

in International Journal of Sports Physiology and Performance

Click name to view affiliation

Marco Machado
Search for other papers by Marco Machado in
Current site
Google Scholar
PubMed
Close
,
Alexander J. Koch
Search for other papers by Alexander J. Koch in
Current site
Google Scholar
PubMed
Close
,
Jeffrey M. Willardson
Search for other papers by Jeffrey M. Willardson in
Current site
Google Scholar
PubMed
Close
,
Frederico C. dos Santos
Search for other papers by Frederico C. dos Santos in
Current site
Google Scholar
PubMed
Close
,
Victor M. Curty
Search for other papers by Victor M. Curty in
Current site
Google Scholar
PubMed
Close
, and
Lucas N. Pereira
Search for other papers by Lucas N. Pereira in
Current site
Google Scholar
PubMed
Close
Restricted access

Purpose:

The purpose of this study was to evaluate the effects of caffeine ingestion before a resistance exercise session on markers of muscle damage (CK, LDH, ALT, AST) and leukocyte levels.

Methods:

Fifteen soccer athletes completed two resistance exercise sessions that differed only in the ingestion of caffeine or a placebo preworkout.

Results:

CK concentration increased significantly following the caffeine session (415.8 ± 62.8 to 542.0 ± 73.5) and the placebo session (411.5 ± 43.3 to 545.8 ± 59.9), with no significant differences between sessions. Similarly, LDH concentration increased significantly following the caffeine session (377.5 ± 18.0 to 580.5 ± 36.1) and the placebo session (384.8 ± 13.9 to 570.4 ± 36.1), with no significant differences between sessions. Both sessions resulted in significant increases in the total leukocyte count (caffeine = 6.24 ± 2.08 to 8.84 ± 3.41; placebo = 6.36 ± 2.34 to 8.77 ± 3.20), neutrophils (caffeine = 3.37 ± 0.13 to 5.15 ± 0.28; placebo = 3.46 ± 0.17 to 5.12 ± 0.24), lymphocytes (caffeine = 2.19 ± 0.091 to 2.78 ± 0.10; placebo = 2.17 ± 0.100 to 2.75 ± 0.11), and monocytes (caffeine = 0.53 ± 0.02 to 0.72 ± 0.06; placebo = 0.56 ± 0.03 to 0.69 ± 0.04), with no significant differences between sessions.

Conclusion:

Ingestion of caffeine at 4.5 mg⋅kg-1 did not augment markers of muscle damage or leukocyte levels above that which occurs through resistance exercise alone.

Machado is with the Laboratory of Physiology and Biokinetic (UNIG Campus V), Itaperuna, Brazil. Koch is with the Health and Exercise Sciences Department, Truman State University, Kirksville, MO. Jeffrey M. Willardson is with the Kinesiology and Sports Studies Department, Eastern Illinois University, Charleston, IL. Dos Santos is with the Laboratory of Physiology and Biokinetic (UNIG Campus V), Itaperuna, Brazil. Curty is with the Laboratory of Physiology and Biokinetic (UNIG Campus V), Itaperuna, Brazil, Pereira is with the Laboratory of Physiology and Biokinetic (UNIG Campus V), Itaperuna, Brazil.

  • Collapse
  • Expand