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The authors compared ACTN3 R577X genotype and allele frequencies in the majority of all-time-best Spanish judo male athletes (n = 108) and 343 ethnically matched nonathletic men. No between-groups differences were found in allele (P = .077) or genotype distributions (P = .178). Thus, the R577X polymorphism was not significantly associated with the status of being an elite judo athlete, at least in the Spanish population. The contribution of genetics to sports-related phenotype traits is undeniable with some genotypes, of which ACTN3 R577X is currently the leading candidate, partly distinguishing individuals predisposed to either endurance or power sports. However, few athletic events can be categorized as purely power or endurance based. Although genetic testing (ie, for ACTN3 R577X) is already being marketed to predict sports talent and potential of young children, its usefulness is still questionable, at least in competitive judo.

Rodríguez-Romo, de Diego, and Díaz de Durana are with the Faculty of Physical Activity and Sport Sciences, Technical University of Madrid, Madrid, Spain. Yvert and Santiago are with the School of Doctoral Research, European University of Madrid, Madrid, Spain. Carratalá is with the Faculty of Physical Activity and Sport Sciences, Valencia University, Valencia, Spain. Garatachea is with the Faculty of Health and Sport Sciences, Zaragoza University, Zaragoza, Spain. Lucia is with the European University and Research Institute (i+12), Madrid, Spain.