The study investigated the effects of 16 weeks of exercise training on s-IgA in a population of low-functioning elderly. Forty-nine volunteers were randomly divided into 4 groups: strength training (ST), aerobic training (AT), a combination (CT), or control (C). ST demonstrated a significant increase in s-IgA from pre to post and a significant increase in the secretion rate from pre to mid and post. AT demonstrated a significant increase in s-IgA from pre to mid to post with no subsequent change in the secretion rate. There were no significant changes across time in CT or C, but C had consistently lower s-IgA values at post than did CT, ST, or AT, and the secretion rate was significantly higher in CT than C at mid and post. The results demonstrate that moderate exercise has a positive effect on mucosal immunity as measured by s-IgA in low-functioning elderly, suggesting a greater resistance to upper respiratory-tract infection with involvement in an exercise program.
Fahlman is with the College of Education, Kinesiology, Health and Sport Studies, Wayne State University, Detroit, MI 48202. Morgan is with the School of HMSLS, Kinesiology, Bowling Green State University, Bowling Green, OH 43403. McNevin is with the Dept. of Physical Therapy, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, MI 48201. Boardley is with the Dept. of PHRS, University of Toledo, Toledo, OH 43606. Topp is with the School of Nursing, University of Louisville, Louisville, KY 40292.