Assessment of habitual physical activity (PA) in patients with heart failure.
This study included 50 patients with heart failure (61.9 ± 4.0 yr). Seven days of PA were assessed by questionnaire (AQ), pedometer, and accelerometer and correlated with prognostic markers including VO2peak, percent left-ventricular ejection fraction, N-terminal pro-B-type natriuretic peptide, and New York Heart Association (NYHA) functional class.
Accelerometry showed a stronger correlation with VO2peak and NYHA class (R = .73 and R = −.68; p < .001) than AQ (R = .58 and R = −.65; p < .001) or pedometer (R = .52 and R = −.50; p < .001). In the multivariable regression model accelerometry was the only consistent independent predictor of VO2peak (p = .002). Moreover, when its accuracy of prediction was tested, 59% of NYHA I and 95% of NYHA III patients were correctly classified into their assigned NYHA classes based on their accelerometer activity.
PA assessed by accelerometer is significantly associated with exercise capacity in patients with heart failure and is predictive of disease severity. The data suggests that PA monitoring can aid in evaluating clinical status.
Jehn, Schmidt-Trucksäss, and Hanssen are with the Institute of Exercise and Health Sciences, University of Basel, Basel, Switzerland. Schuster is with the Institute for Medical Statistics and Epidemiology, and Halle, the Dept. of Prevention, Rehabilitation and Sports Medicine, Technical University of Munich, Munich, Germany. Koehler is with the Dept. of Cardiology and Angiology, Charité University Berlin, Berlin, Germany.