This study aimed to determine the effects of physical-exercise-based rehabilitation programs on quality of life of patients with Parkinson’s disease through a systematic review of randomized clinical trials. For this purpose the following electronic databases were selected: Medline by PubMed, Cochrane, Web of Science, and PEDro. The search strategy included the proposed descriptors in the Medical Subject Headings (MeSH), associated with a sensitive list of terms to search for randomized controlled trials (RCTs), without year and language restrictions. Fourteen studies were potentially relevant, and these studies were included. Physical-exercise-based rehabilitation programs realized 2–4 times a week, 60 min each session, for 6–12 weeks, and follow-up of 3 months promotes significant positive effects on quality of life in Parkinson’s disease patients at mild to moderate stages and disease duration around 6 years.
Cascaes da Silva, da Rosa Iop, Domingos dos Santos, and da Silva are with the University of State of Santa Catarina, Center for Health Sciences and Sports, Adapted Physical Activity Laboratory, Florianópolis, SC, Brazil. Aguiar Bezerra de Melo and Barbosa Gutierres Filho are with the University of Brasilia, Faculty of Physical Education, Brasilia, Brazil.