Aging and Recovery After Resistance-Exercise-Induced Muscle Damage: Current Evidence and Implications for Future Research

in Journal of Aging and Physical Activity

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John F.T. Fernandes
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Kevin L. Lamb
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Jonathan P. Norris
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Jason Moran
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Benjamin Drury
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Nattai R. Borges
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Craig Twist
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DOI:
https://doi.org/10.1123/japa.2020-0201
Keywords:
dynapenia; fatigue; muscle soreness; muscle strength; sarcopenia
First Published Online:
08 Dec 2020
In Print:
Volume 29: Issue 3
Page Range:
544–551
Restricted access

Aging is anecdotally associated with a prolonged recovery from resistance training, though current literature remains equivocal. This brief review considers the effects of resistance training on indirect markers of muscle damage and recovery (i.e., muscle soreness, blood markers, and muscle strength) in older males. With no date restrictions, four databases were searched for articles relating to aging, muscle damage, and recovery. Data from 11 studies were extracted for review. Of these, four reported worse symptoms in older compared with younger populations, while two have observed the opposite, and the remaining studies (n = 6) proposed no differences between age groups. It appears that resistance training can be practiced in older populations without concern for impaired recovery. To improve current knowledge, researchers are urged to utilize more ecologically valid muscle-damaging bouts and investigate the mechanisms which underpin the recovery of muscle soreness and strength after exercise in older populations.

Fernandes and Drury are with the Higher Education Sport, Hartpury University, Hartpury, United Kingdom. Lamb and Twist are with the Department of Sport and Exercise Sciences, University of Chester, Chester, United Kingdom. Norris is with the Derbyshire County Cricket Club, Derby, United Kingdom. Moran is with the School of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, United Kingdom. Borges is with the School of Environmental and Life Sciences, The University of Newcastle, Newcastle, Australia.

Fernandes (jfmtfernandes@hotmail.co.uk) is corresponding author.
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  • Allen, D.G., Lamb, G.D., & Westerblad, H. (2008). Skeletal muscle fatigue: Cellular mechanisms. Physiological Reviews, 88(1), 287–332. PubMed ID: 18195089 doi:10.1152/physrev.00015.2007

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Allison, S.J., Brooke-Wavell, K., & Folland, J.P. (2013). Multiple joint muscle function with ageing: The force–velocity and power–velocity relationships in young and older men. Aging Clinical and Experimental Research, 25(2), 159–166. PubMed ID: 23739901 doi:10.1007/s40520-013-0024-y

    • Crossref
    • Search Google Scholar
    • Export Citation

  • American College of Sports Medicine. (2002). Progression models in resistance training for healthy adults. Medicine & Science in Sports & Exercise, 34(2), 364–380. doi:10.1097/00005768-200202000-00027

    • Search Google Scholar
    • Export Citation

  • American College of Sports Medicine. (2009). Progression models in resistance training for healthy adults. Medicine & Science in Sports & Exercise, 41(3), 687–708. doi:10.1249/MSS.0b013e3181915670

    • Search Google Scholar
    • Export Citation

  • Arroyo, E., Wells, A.J., Gordon, J.A., Varanoske, A.N., Gepner, Y., Coker, N.A., . . . Hoffman, J.R. (2017). Tumor necrosis factor-alpha and soluble TNF-alpha receptor responses in young vs. middle-aged males following eccentric exercise. Experimental Gerontology, 100, 28–35. doi:10.1016/j.exger.2017.10.012

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Avela, J., Kyröläinen, H., Komi, P.V, & Rama, D. (1999). Reduced reflex sensitivity persists several days after long-lasting stretch-shortening cycle exercise. Journal of Applied Physiology, 86(4), 1292–1300. PubMed ID: 10194215 doi:10.1152/jappl.1999.86.4.1292

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Baker, A.B., & Tang, Y.Q. (2010). Aging performance for masters records in athletics, swimming, rowing, cycling, triathlon, and weightlifting. Experimental Aging Research, 36(4), 453–477. PubMed ID: 20845122 doi:10.1080/0361073X.2010.507433

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Balcombe, N.R., & Sinclair, A. (2001). Ageing: Definitions, mechanisms and the magnitude of the problem. Best Practice and Research in Clinical Gastroenterology, 15(6), 835–849. doi:10.1053/bega.2001.0244

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Bottaro, M., Machado, S.N., Nogueira, W., Scales, R., & Veloso, J. (2007). Effect of high versus low-velocity resistance training on muscular fitness and functional performance in older men. European Journal of Applied Physiology, 99(3), 257–264. PubMed ID: 17146693 doi:10.1007/s00421-006-0343-1

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Buford, T.W., MacNeil, R.G., Clough, L.G., Dirain, M., Sandesara, B., Pahor, M., . . . Leeuwenburgh, C. (2014). Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults. Journal of Applied Physiology, 116(11), 1481–1490. PubMed ID: 23493365 doi:10.1152/japplphysiol.01350.2012

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Burt, D., Lamb, K., Nicholas, C., & Twist, C. (2015). Lower-volume muscle-damaging exercise protects against high-volume muscle-damaging exercise and the detrimental effects on endurance performance. European Journal of Applied Physiology, 115(7), 1523–1532. PubMed ID: 25697150 doi:10.1007/s00421-015-3131-y

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Byrne, C., Twist, C., & Eston, R. (2004). Neuromuscular function after exercise-induced muscle damage: Theoretical and applied implications. Sports Medicine, 34(1), 49–69. PubMed ID: 14715039 doi:10.2165/00007256-200434010-00005

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Chapman, D.W., Newton, M., McGuigan, M.R., & Nosaka, K. (2008). Comparison between old and young men for responses to fast velocity maximal lengthening contractions of the elbow flexors. European Journal of Applied Physiology, 104(3), 531–539. PubMed ID: 18584196 doi:10.1007/s00421-008-0806-7

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Chen, T.C., Lin, K.Y., Chen, H.L., Lin, M.J., & Nosaka, K. (2011). Comparison in eccentric exercise-induced muscle damage among four limb muscles. European Journal of Applied Physiology, 111(2), 211–223. PubMed ID: 20852880 doi:10.1007/s00421-010-1648-7

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Chen, T.C., Yang, T.J., Huang, M.J., Wang, H.S., Tseng, K.W., Chen, H.L., & Nosaka, K. (2019). Damage and the repeated bout effect of arm, leg, and trunk muscles induced by eccentric resistance exercises. Scandinavian Journal of Medicine & Science in Sports, 29(5), 725–735. PubMed ID: 30663816 doi:10.1111/sms.13388

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Clark, B.C., & Manini, T.M. (2008). Sarcopenia ≠ dynapenia. Journal of Gerontology: Medical Sciences, 63(8), 829–834.

  • Clark, B.C., & Manini, T.M. (2012). What is dynapenia? Nutrition, 28(5), 495–503. PubMed ID: 22469110 doi:10.1016/j.nut.2011.12.002

  • Clarkson, P.M., & Dedrick, M.E. (1988). Exercise-induced muscle damage, repair, and adaptation in old and young subjects. Journal of Gerontology, 43(4), M91–M96. doi:10.1093/geronj/43.4.M91

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Clifford, T. (2019). Nutritional and pharmacological interventions to expedite recovery following muscle-damaging exercise in older adults: A narrative review of the literature. Journal of Aging and Physical Activity, 27(4), 914–928.

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Cronin, J.B., & Hansen, K.T. (2005). Strength and power predictors of sports speed. Journal of Strength & Conditioning Research, 19(2), 349–357. PubMed ID: 15903374

    • Search Google Scholar
    • Export Citation

  • Cruz-Jentoft, A.J., Baeyens, J.P., Bauer, J.M., Boirie, Y., Cederholm, T., Landi, F., . . . Zamboni, M. (2010). Sarcopenia: European consensus on definition and diagnosis. Age and Ageing, 39(4), 412–423. PubMed ID: 20392703 doi:10.1093/ageing/afq034

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Dalton, B.H., Power, G.A., Paturel, J.R., & Rice, C.L. (2015). Older men are more fatigable than young when matched for maximal power and knee extension angular velocity is unconstrained. Age, 37(3), 1–16. doi:10.1007/s11357-015-9790-0

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Dalton, B.H., Power, G.A., Vandervoort, A.A., & Rice, C.L. (2012). The age-related slowing of voluntary shortening velocity exacerbates power loss during repeated fast knee extensions. Experimental Gerontology, 47(1), 85–92. PubMed ID: 22079852 doi:10.1016/j.exger.2011.10.010

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Damas, F., Nosaka, K., Libardi, C.A., Chen, T.C., & Ugrinowitsch, C. (2016). Susceptibility to exercise-induced muscle damage: A cluster analysis with a large sample. International Journal of Sports Medicine, 37(8), 633–640. PubMed ID: 27116346 doi:10.1055/s-0042-100281

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Dannecker, E.A., Liu, Y., Rector, R.S., Thomas, T.R., Fillingim, R.B., & Robinson, M.E. (2012). Sex differences in exercise-induced muscle pain and muscle damage. Journal of Pain, 13(12), 1242–1249. PubMed ID: 23182229 doi:10.1016/j.jpain.2012.09.014

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Dedrick, M.E., & Clarkson, P.M. (1990). The effects of eccentric exercise on motor performance in young and older women. European Journal of Applied Physiology, 60(3), 183–186. doi:10.1007/BF00839156

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Department of Health and Social Care. (2019). UK chief medical officers’ physical activity guidelines. Department of Health and Social Care, Llwodraeth Cymru Welsh Government, Department of Health Northern Ireland and the Scottish Government. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/832868/uk-chief-medical-officers-physical-activity-guidelines.pdf

    • Search Google Scholar
    • Export Citation

  • Doguet, V., Jubeau, M., Dorel, S., Couturier, A., Lacourpaille, L., Guével, A., & Guilhem, G. (2016). Time-course of neuromuscular changes during and after maximal eccentric contractions. Frontiers in Physiology, 7, 1–8.

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fell, J., & Williams, A.D. (2008). The effect of aging on skeletal-muscle recovery from exercise: Possible implications for aging athletes. Journal of Aging and Physical Activity, 16(1), 97–115. PubMed ID: 18268815 doi:10.1123/japa.16.1.97

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fernandes, J.F.T., Daniels, M., Myler, L., & Twist, C. (2019). Influence of playing standard on upper- and lower-body strength, power, and velocity characteristics of elite rugby league players. Journal of Functional Morphology and Kinesiology, 4(2), 22. doi:10.3390/jfmk4020022

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fernandes, J.F.T., Lamb, K.L., & Twist, C. (2018a). A comparison of load–velocity and load–power relationships between well-trained young and middle-aged males during three popular resistance exercises. Journal of Strength & Conditioning Research, 32(5), 1440–1447. doi:10.1519/JSC.0000000000001986

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fernandes, J.F.T., Lamb, K.L., & Twist, C. (2018b). Internal loads, but not external loads and fatigue, are similar in young and middle-aged resistance-trained males during high volume squatting exercise. Journal of Functional Morphology and Kinesiology, 3(3), 45. doi:10.3390/jfmk3030045

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fernandes, J.F.T., Lamb, K.L., & Twist, C. (2019). Exercise-induced muscle damage and recovery in young and middle-aged males with different resistance training experience. Sports, 7(6), 132. doi:10.3390/sports7060132

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Ferrucci, L., Giallauria, F., & Guralnik, J.M. (2008). Epidemiology of aging. Radiologic Clinics of North America, 46(4), 643–652. PubMed ID: 18922285 doi:10.1016/j.rcl.2008.07.005

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Fridén, J., & Lieber, R.L. (2001). Serum creatine kinase level is a poor predictor of muscle function after injury. Scandinavian Journal of Medicine & Science in Sports, 11(2), 126–127. PubMed ID: 11252462

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Frontera, W.R., Suh, D., Krivickas, L.S., Hughes, V.A., Goldstein, R., & Roubenoff, R. (2000). Skeletal muscle fiber quality in older men and women. American Journal of Physiology—Cell Physiology, 279(3), C611–C618. PubMed ID: 10942711 doi:10.1152/ajpcell.2000.279.3.C611

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Gordon, J., III, Hoffman, J.R., Arroyo, E., Varanoske, A., Coker, N., Gepner, Y., . . . Fukuda, D. (2017). Comparisons in the recovery response from resistance exercise between young and middle-aged men. Journal of Strength & Conditioning Research, 31(12), 3454–3462. PubMed ID: 28859014 doi:10.1519/JSC.0000000000002219

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Hansen, K.T., Cronin, J.B., Pickering, S.L., & Douglas, L. (2011). Do force–time and power–time measures in a loaded jump squat differentiate between speed performance and playing level in elite and elite junior rugby union players? Journal of Strength & Conditioning Research, 25(9), 2382–2391. doi:10.1519/JSC.0b013e318201bf48

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Heckel, Z., Atlasz, T., Tékus, É., Kőszegi, T., Laczkó, J., & Váczi, M. (2019). Monitoring exercise-induced muscle damage indicators and myoelectric activity during two weeks of knee extensor exercise training in young and old men. PLoS One, 14(11), e0224866. doi:10.1371/journal.pone.0224866

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Highton, J.M., Twist, C., & Eston, R.G. (2009). The effects of exercise-induced muscle damage on agility and sprint running performance. Journal of Exercise Science & Fitness, 7(1), 24–30. doi:10.1016/S1728-869X(09)60004-6

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Horita, T., Komi, P.V., Nicol, C., & Kyröläinen, H. (1999). Effect of exhausting stretch-shortening cycle exercise on the time course of mechanical behaviour in the drop jump: Possible role of muscle damage. European Journal of Applied Physiology and Occupational Physiology, 79(2), 160–167. PubMed ID: 10029337 doi:10.1007/s004210050490

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Hortobágyi, T., Houmard, J., Fraser, D., Dudek, R., Lambert, J., & Tracy, J. (1998). Normal forces and myofibrillar disruption after repeated eccentric exercise. Journal of Applied Physiology, 84(2), 492–498. PubMed ID: 9475858 doi:10.1152/jappl.1998.84.2.492

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Hubal, M.J., Rubinstein, S.R., & Clarkson, P.M. (2007). Mechanisms of variability in strength loss after muscle-lengthening actions. Medicine & Science in Sports & Exercise, 39(3), 461–468. PubMed ID: 17473772 doi:10.1249/01.mss.0000247007.19127.da

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Hyldahl, R.D., & Hubal, M.J. (2014). Lengthening our perspective: Morphological, cellular, and molecular responses to eccentric exercise. Muscle and Nerve, 49(2), 155–170. PubMed ID: 24030935 doi:10.1002/mus.24077

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Hyldahl, R.D., Chen, T.C., & Nosaka, K. (2017). Mechanisms and mediators of the skeletal muscle repeated bout effect. Exercise and Sport Sciences Reviews, 45(1), 24–33. PubMed ID: 27782911 doi:10.1249/JES.0000000000000095

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Jamurtas, A.Z., Theocharis, V., Tofas, T., Tsiokanos, A., Yfanti, C., Paschalis, V., . . . Nosaka, K. (2005). Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. European Journal of Applied Physiology, 95(2–3), 179–185. PubMed ID: 16007451 doi:10.1007/s00421-005-1345-0

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Jones, D.A., Newham, D.J., & Torgan, C. (1989). Mechanical influences on long-lasting human muscle fatigue and delayed onset pain. The Journal of Physiology, 412(1), 415–427. doi:10.1113/jphysiol.1989.sp017624

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Kongsgaard, M., Backer, V., Jørgensen, K., Kjær, M., & Beyer, N. (2004). Heavy resistance training increases muscle size, strength and physical function in elderly male COPD-patients—A pilot study. Respiratory Medicine, 98(10), 1000–1007. PubMed ID: 15481277 doi:10.1016/j.rmed.2004.03.003

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Lavender, A.P., & Nosaka, K. (2006). Comparison between old and young men for changes in makers of muscle damage following voluntary eccentric exercise of the elbow flexors. Applied Physiology, Nutrition, and Metabolism, 31(3), 218–225. PubMed ID: 16770348 doi:10.1139/h05-028

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Lavender, A.P., & Nosaka, K. (2007). Fluctuations of isometric force after eccentric exercise of the elbow flexors of young, middle-aged, and old men. European Journal of Applied Physiology, 100(2), 161–167. PubMed ID: 17310389 doi:10.1007/s00421-007-0418-7

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Lavender, A.P., & Nosaka, K. (2008). Changes in markers of muscle damage of middle-aged and young men following eccentric exercise of the elbow flexors. Journal of Science and Medicine in Sport, 11(2), 124–131. PubMed ID: 17350334 doi:10.1016/j.jsams.2006.11.004

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Lepers, R. (2019). Sex difference in triathlon performance. Frontiers in Physiology, 10, 1–7.

  • Lepers, R., & Stapley, P.J. (2016). Master athletes are extending the limits of human endurance. Frontiers in Physiology, 7, 1–8.

  • Lepers, R., Rüst, C.A., Stapley, P.J., & Knechtle, B. (2013). Relative improvements in endurance performance with age: Evidence from 25 years of Hawaii Ironman racing. Age, 35(3), 953–962. PubMed ID: 22367579 doi:10.1007/s11357-012-9392-z

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Lexell, J. (1995). Human aging, muscle mass, and fiber type composition. The Journals of Gerontology, Series A: Biological Sciences & Medical Sciences, 50, 11–16.

    • Search Google Scholar
    • Export Citation

  • Lexell, J., Taylor, C.C., & Sjöström, M. (1988). What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. Journal of the Neurological Sciences, 84(2–3), 275–294. PubMed ID: 3379447 doi:10.1016/0022-510X(88)90132-3

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Macdonald, G.Z., Button, D.C., Drinkwater, E.J., & Behm, D.G. (2014). Foam rolling as a recovery tool after an intense bout of physical activity. Medicine & Science in Sports & Exercise, 46(1), 131–142. PubMed ID: 24343353 doi:10.1249/MSS.0b013e3182a123db

    • Crossref
    • Search Google Scholar
    • Export Citation

  • McHugh, M.P. (2003). Recent advances in the understanding of the repeated bout effect: The protective effect against muscle damage from a single bout of eccentric exercise. Scandinavian Journal of Medicine & Science in Sports, 13(2), 88–97. PubMed ID: 12641640 doi:10.1034/j.1600-0838.2003.02477.x

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Minett, G.M., & Duffield, R. (2014). Is recovery driven by central or peripheral factors? A role for the brain in recovery following intermittent-sprint exercise. Frontiers in Physiology, 5, 1–9.

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Morgan, D.L., & Proske, U. (2004). Popping sarcomere hypothesis explains stretch-induced muscle damage. Clinical and Experimental Pharmacology and Physiology, 31(8), 541–545. PubMed ID: 15298548 doi:10.1111/j.1440-1681.2004.04029.x

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Morton, J.P., Atkinson, G., MacLaren, D.P.M., Cable, N.T., Gilbert, G., Broome, C., . . . Drust, B. (2005). Reliability of maximal muscle force and voluntary activation as markers of exercise-induced muscle damage. European Journal of Applied Physiology, 94(5–6), 541–548. PubMed ID: 15928932 doi:10.1007/s00421-005-1373-9

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Newton, R.U., Häkikinen, K., Häkikinen, A., Mccormick, M., Volek, J., & Kraemer, W. (2002). Mixed-methods of resistance training increases power and strength of young and older men. Medicine & Science in Sports & Exercise, 34(8), 1367–1375. PubMed ID: 12165694 doi:10.1097/00005768-200208000-00020

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Nikolaidis, M. (2017). The effects of resistance exercise on muscle damage, position sense, and blood redox status in young and elderly individuals. Geriatrics, 2(3), 20. doi:10.3390/geriatrics2030020

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Nikolaidis, M., Kyparos, A., Spanou, C., Paschalis, V., Theodorou, A.A., Panayiotou, G., . . . Vrabas, I.S. (2013). Aging is not a barrier to muscle and redox adaptations: Applying the repeated eccentric exercise model. Experimental Gerontology, 48(8), 734–743. PubMed ID: 23628501 doi:10.1016/j.exger.2013.04.009

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Nogueira, F.R.D., Libardi, C.A., Nosaka, K., Vechin, F.C., Cavaglieri, C.R., & Chacon-Mikahil, M.P.T. (2014). Comparison in responses to maximal eccentric exercise between elbow flexors and knee extensors of older adults. Journal of Science and Medicine in Sport, 17(1), 91–95. PubMed ID: 23499318 doi:10.1016/j.jsams.2013.02.002

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Nosaka, K., Newton, M., & Sacco, P. (2002). Delayed-onset muscle soreness does not reflect the magnitude of eccentric exercise-induced muscle damage. Scandinavian Journal of Medicine & Science in Sports, 12(6), 337–346. PubMed ID: 12453160 doi:10.1034/j.1600-0838.2002.10178.x

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Orimo, H., Ito, H., Suzuki, T., Araki, A., Hosoi, T., & Sawabe, M. (2006). Reviewing the definition of elderly. Geriatrics and Gerontology International, 43(1), 27–34.

    • Search Google Scholar
    • Export Citation

  • Owens, D.J., Twist, C., Cobley, J.N., Howatson, G., & Close, G.L. (2018). Exercise-induced muscle damage: What is it, what causes it and what are the nutritional solutions? European Journal of Sport Science, 19(4), 1–15. doi:10.1080/17461391.2018.1505957

    • Search Google Scholar
    • Export Citation

  • Pantoja, P.D., Saez De Villarreal, E., Brisswalter, J., Peyré-Tartaruga, L.A., & Morin, J.B. (2016). Sprint acceleration mechanics in masters athletes. Medicine & Science in Sports & Exercise, 48(12), 2469–2476. PubMed ID: 27414690 doi:10.1249/MSS.0000000000001039

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Paulsen, G., Mikkelsen, U.R., Raastad, T., & Peake, J.M. (2012). Leucocytes, cytokines and satellite cells: What role do they play in muscle damage and regeneration following eccentric exercise? Exercise Immunology Review, 18, 42–97. PubMed ID: 22876722

    • Search Google Scholar
    • Export Citation

  • Petrella, J.K., Kim, J., Tuggle, S.C., Hall, S.R., & Bamman, M.M. (2005). Age differences in knee extension power, contractile velocity, and fatigability. Journal of Applied Physiology, 98(1), 211–220. PubMed ID: 15347625 doi:10.1152/japplphysiol.00294.2004

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Ploutz-Snyder, L.L., Giamis, E.L., Formikell, M., & Rosenbaum, A.E. (2001). Resistance training reduces susceptibility to eccentric exercise-induced muscle dysfunction in older women. Journal of Gerontology: Biological Sciences, 56(9), 384–390.

    • Search Google Scholar
    • Export Citation

  • Power, G.A., Dalton, B.H., Rice, C.L., & Vandervoort, A.A. (2012). Power loss is greater following lengthening contractions in old versus young women. Age, 34(3), 737–750. PubMed ID: 21559865 doi:10.1007/s11357-011-9263-z

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Roth, S.M., Martel, G.F., Ivey, F.M., Lemmer, J.T., Tracy, B.L., Hurlbut, D.E., . . . Rogers, M.A. (1999). Ultrastructural muscle damage in young vs. older men after high-volume, heavy-resistance strength training. Journal of Applied Physiology, 86(6), 1833–1840. PubMed ID: 10368346 doi:10.1152/jappl.1999.86.6.1833

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Saka, T., Akova, B., Yazici, Z., Sekir, U., Gür, H., & Ozarda, Y. (2009). Difference in the magnitude of muscle damage between elbow flexors and Knee extensors eccentric exercises. Journal of Sports Science & Medicine, 8(1), 107–115. PubMed ID: 24150563

    • Search Google Scholar
    • Export Citation

  • Sayers, S.P., & Clarkson, P.M. (2001). Force recovery after eccentric exercise in males and females. European Journal of Applied Physiology, 84(1–2), 122–126. PubMed ID: 11394240 doi:10.1007/s004210000346

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Sayers, S.P., & Gibson, K. (2010). A comparison of high-speed power training and traditional slow-speed resistance training in older men and women. Journal of Strength & Conditioning Research, 24(12), 3369–3380. PubMed ID: 21068681 doi:10.1519/JSC.0b013e3181f00c7c

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Sayers, S.P., & Gibson, K. (2014). High-speed power training in older adults: A shift of the external resistance at which peak power is produced. Journal of Strength & Conditioning Research, 28(3), 616–621. PubMed ID: 23897022 doi:10.1519/JSC.0b013e3182a361b8

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Schoenfeld, B.J. (2010). The mechanisms of muscle hypertrophy and their application to resistance training. Journal of Strength & Conditioning Research, 24(10), 2857–2872. PubMed ID: 20847704 doi:10.1519/JSC.0b013e3181e840f3

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Sewright, K.A., Hubal, M.J., Kearns, A., Holbrook, M.T., & Clarkson, P.M. (2008). Sex differences in response to maximal eccentric exercise. Medicine & Science in Sports & Exercise, 40(2), 242–251. PubMed ID: 18202579 doi:10.1249/mss.0b013e31815aedda

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Sorichter, S., Puschendorf, B., & Mair, J. (1999). Skeletal muscle injury induced by eccentric muscle action: Muscle proteins as markers of muscle fiber injury. Exercise Immunology Review, 5, 5–21. PubMed ID: 10519060

    • Search Google Scholar
    • Export Citation

  • Stupka, N., Tarnopolsky, M.A., Yardley, N.J., & Phillips, S.M. (2017). Cellular adaptation to repeated eccentric exercise-induced muscle damage. Journal of Applied Physiology, 91(4), 1669–1678. doi:10.1152/jappl.2001.91.4.1669

    • Crossref
    • Search Google Scholar
    • Export Citation

  • Tanaka, H., & Seals, D.R. (2008). Endurance exercise performance in Masters athletes: Age-associated changes and underlying physiological mechanisms. Journal of Physiology, 586(1), 55–63. PubMed ID: 17717011 doi:10.1113/jphysiol.2007.141879

    • Crossref
    • Search Google Scholar
    • Export Citation

  • United Nations, Department of Economic and Social Affairs. (2017). World population prospects: The 2017 revision. Working Paper No. ESA/P/WP/248. New York, NY: Author. https://population.un.org/wpp/Publications/Files/WPP2017_KeyFindings.pdf

    • Search Google Scholar
    • Export Citation

  • Warren, G., Lowe, D., & Armstrong, R. (1999). Measurement tools used in the study of eccentric contraction-induced injury. Sports Medicine, 27(1), 43–59. PubMed ID: 10028132 doi:10.2165/00007256-199927010-00004

    • Crossref
    • Search Google Scholar
    • Export Citation
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