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Leisure activities, particularly physically and cognitively stimulating leisure activities, mitigate cognitive decline. The present study aimed to examine the relationship between mahjong playing, leisure physical activity, and mild cognitive impairment (MCI). Older adults with and without MCI were recruited (n = 489, healthy group; and n = 187, MCI group). The regression results showed that years of mahjong playing (odds ratio = 0.595, 95% confidence interval [0.376, 0.961], p = .032) and physical activity (odds ratio = 0.572, 95% confidence interval [0.381, 0.849], p = .012) were associated with reduced odds of having MCI after adjusting for a series of covariates. Leisure physical activity and mahjong playing interacted with each other and produced combined effects on the odds of having MCI. Combined cognitive and physical interventions may produce larger benefits on cognition than either intervention alone.
Ding and Ouyang contributed equally to this work. Ding, Zhang, Jiang, and Tao are with the Department of Public Health and Preventive Medicine, School of Basic Medicine, Jinan University, Guangzhou, Guangdong, China; and the Division of Medical Psychology and Behavior Science, School of Basic Medicine, Jinan University, Guangzhou, Guangdong, China. Ouyang is with the Department of Rehabilitation Medicine, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China. Zhuang is with the Shenzhen Health Education and Promotion Center, Shenzhen, China. Dong is with the Division of Epidemiology, School of Basic Medicine, Jinan University, Guangzhou, Guangdong, China. Chen is with the Department of Primary Public Health, Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China. Yang is with the Yuancun Huayin Community Health Service Station, Guangzhou, Guangdong, China.