The Association of Self-Reported Muscle-Strengthening Activities With Carotid Intima–Media Thickness in Older Adults: Cooper Center Longitudinal Study

in Journal of Aging and Physical Activity
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The purpose of the current investigation was to examine the cross-sectional associations of participation in muscle-strengthening activities (MSAs) with carotid intima–media thickness (CIMT) among older adults. The data are from 2,557 older adult participants enrolled in an observational cohort who reported no history of cardiovascular disease. MSA was determined using a questionnaire. Carotid ultrasound was performed to measure the CIMT of the common carotid artery bilaterally. Logistic regression models were constructed to estimate the association of MSA with CIMT after adjustment for potential confounders. The participants were aged 68.6 ± 7.0 years, and the majority were male (71.7%) and White (96.5%); 18% had abnormal CIMT. Meeting the physical activity guidelines for MSA was inversely associated with abnormal CIMT after adjustment for age and sex. However, this observed inverse relation became statistically null after further adjustment for cardiovascular disease risk factors, including aerobic physical activity.

J. Lee, Kohl, and Gabriel are with the Department of Epidemiology, Human Genetics and Environmental Sciences, Michael & Susan Dell Center for Healthy Living, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Austin, TX, USA. Chen is with the Department of Biostatistics and Data Science, Michael & Susan Dell Center for Healthy Living, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Austin, TX, USA. Kohl and Gabriel are also with the Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX, USA. Barlow and DeFina are with The Cooper Institute, Dallas, TX, USA. Radford is with Cooper Clinic, Dallas, TX, USA. C.D. Lee is with the School of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ, USA. Gabriel is also with the Department of Women’s Health, Dell Medical School, The University of Texas at Austin, Austin, TX, USA. J. Lee is also with the Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA. J.

Lee (lee8690@bu.edu) is corresponding author.
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