Changes in Strength, Mobility, and Body Composition Following Self-Selected Exercise in Older Adults

in Journal of Aging and Physical Activity
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The purpose of this trial was to examine the effects of self-selected exercise intensities plus either whey protein or placebo supplementation on vital signs, body composition, bone mineral density, muscle strength, and mobility in older adults. A total of 101 participants aged 55 years and older (males [n = 34] and females [n = 67]) were evaluated before and after 12 weeks of self-selected, free-weight resistance exercise plus 30 min of self-paced walking three times per week. The participants were randomized into two groups: whey protein (n = 46) or placebo (n = 55). Three-way mixed factorial analyses of variance were used to test for mean differences for each variable. The 12 weeks of self-selected, self-paced exercise intensities improved resting heart rate, fat-free mass, percent body fat, handgrip strength, bench press strength, leg press strength, and all mobility measurements (p < .05) in males and females despite supplementation status. This suggests that additional protein in well-fed healthy older adults does not enhance the benefit of exercise.

A.A. Herda and T.J. Herda are with the Department of Health, Sport, and Exercise Sciences, The University of Kansas, Lawrence, KS, USA. McKay is with the Physician Assistant Program, School of Medicine, Creighton University, Omaha, NE, USA. Costa is with the Department of Kinesiology, California State University, Fullerton, CA, USA. Stout is with the School of Kinesiology and Physical Therapy, University of Central Florida, Orlando, FL, USA. Cramer is with the Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE, USA.

A.A. Herda (a.herda@ku.edu) is corresponding author.
  • Balachandran, A., Martins, M.M., De Faveri, F.G., Alan, O., Cetinkaya, F., & Signorile, J.F. (2016). Functional strength training: Seated machine vs. standing cable training to improve physical function in elderly. Experimental Gerontology, 82, 131138. PubMed ID: 27354031 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A.J., Morley, J.E., . . . Boirie, Y. (2013). Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the PROT-AGE study group. Journal of the American Medical Directors Association, 14(8), 542559. PubMed ID: 23867520 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Baugreet, S., Hamill, R.M., Kerry, J.P., & McCarthy, S.N. (2017). Mitigating nutrition and health deficiencies in older adults: A role for food innovation? Journal of Food Science, 82(4), 848855. PubMed ID: 28267864 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Brassington, G.S., Atienza, A.A., Perczek, R.E., DiLorenzo, T.M., & King, A.C. (2002). Intervention-related cognitive versus social mediators of exercise adherence in the elderly. American Journal of Preventive Medicine, 23(2, Suppl. 1), 8086. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Campbell, W.W., Crim, M.C., Young, V.R., & Evans, W.J. (1994). Increased energy requirements and changes in body composition with resistance training in older adults. The American Journal of Clinical Nutrition, 60(2), 167175. PubMed ID: 8030593 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Carmeli, E., Reznick, A.Z., Coleman, R., & Carmeli, V. (2000). Muscle strength and mass of lower extremities in relation to functional abilities in elderly adults. Gerontology, 46(5), 249257. PubMed ID: 10965180 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Chen, L.-K., Liu, L.-K., Woo, J., Assantachai, P., Auyeung, T.-W., & Bahyah, K.S. (2014). Sarcopenia in Asia: Consensus report of the Asian working group for sarcopenia. Journal of the American Medical Directors Association, 15(2), 95101. PubMed ID: 24461239 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Clark, M.G., Rattigan, S., & Barrett, E.J. (2006). Nutritive blood flow as an essential element supporting muscle anabolism. Current Opinion in Clinical Nutrition and Metabolic Care, 9(3), 185189. PubMed ID: 16607114 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Coetsee, C., & Terblanche, E. (2017). The effect of three different exercise training modalities on cognitive and physical function in a healthy older population. European Review of Aging and Physical Activity, 14(1), 13. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Copeland, J.L., Good, J., & Dogra, S. (2019). Strength training is associated with better functional fitness and perceived healthy aging among physically active older adults: A cross-sectional analysis of the Canadian longitudinal study on aging. Aging Clinical and Experimental Research, 31(9), 12571263. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Cramer, J.T., Cruz-Jentoft, A.J., Landi, F., Hickson, M., Zamboni, M., Pereira, S.L., . . . Mustad, V.A. (2016). Impacts of high-protein oral nutritional supplements among malnourished men and women with sarcopenia: A multicenter, randomized, double-blinded, controlled trial. Journal of the American Medical Directors Association, 17(11), 10441055. PubMed ID: 27780567 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Cress, M.E., Buchner, D.M., Questad, K.A., Esselman, P.C., deLateur, B.J., & Schwartz, R.S. (1999). Exercise: Effects on physical functional performance in independent older adults. The Journals of Gerontology, Series A: Biological Sciences & Medical Sciences, 54(5), M242M248. PubMed ID: 10362007 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Cruz-Jentoft, A.J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., . . . Zamboni, M. (2019). Sarcopenia: Revised European consensus on definition and diagnosis. Age and Ageing, 48(1), 1631. PubMed ID: 30312372 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Cruz-Jentoft, A.J., Landi, F., Schneider, S.M., Zúñiga, C., Arai, H., Boirie, Y., . . . Cederholm, T. (2014). Prevalence of and interventions for sarcopenia in ageing adults: A systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age and Ageing, 43(6), 748759. PubMed ID: 25241753 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Daly, R.M. (2017). Exercise and nutritional approaches to prevent frail bones, falls and fractures: An update. Climacteric, 20(2), 119124. PubMed ID: 28286988 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Deutz, N.E.P., Ashurst, I., Ballesteros, M.D., Bear, D.E., Cruz-Jentoft, A.J., Genton, L., . . . Prado, C.M. (2019). The underappreciated role of low muscle mass in the management of malnutrition. Journal of the American Medical Directors Association, 20(1), 2227. PubMed ID: 30580819 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Deutz, N.E.P., Bauer, J.M., Barazzoni, R., Biolo, G., Boirie, Y., Bosy-Westphal, A., . . . Calder, P.C. (2014). Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN expert group. Clinical Nutrition, 33(6), 929936. PubMed ID: 24814383 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Dodds, R.M., Roberts, H.C., Cooper, C., & Sayer, A.A. (2015). The epidemiology of sarcopenia. Journal of Clinical Densitometry, 18(4), 461466. PubMed ID: 32224102 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Donini, L.M., Savina, C., & Cannella, C. (2003). Eating habits and appetite control in the elderly: The anorexia of aging. International Psychogeriatrics, 15(1), 7387. PubMed ID: 12834202 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Elsangedy, H.M., Krinski, K., Machado, D.G., Agrícola, P.M., Okano, A.H., & Gregório da Silva, S. (2016). Self-selected intensity, ratings of perceived exertion, and affective responses in sedentary male subjects during resistance training. Journal of Physical Therapy Science, 28(6), 17951800. PubMed ID: 27390418 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Elsangedy, H.M., Krause, M.P., Krinski, K., Alves, R.C., Hsin Nery Chao, C., & da Silva, S.G. (2013). Is the self-selected resistance exercise intensity by older women consistent with the American College of Sports Medicine guidelines to improve muscular fitness? Journal of Strength and Conditioning Research, 27(7), 18771884. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Fielding, R.A., Vellas, B., Evans, W.J., Bhasin, S., Morley, J.E., Newman, A.B., . . . Zamboni, M. (2011). Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia. Journal of the American Medical Directors Association, 12(4), 249256. PubMed ID: 21527165 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Finger, D., Goltz, F.R., Umpierre, D., Meyer, E., Rosa, L.H.T., & Schneider, C.D. (2015). Effects of protein supplementation in older adults undergoing resistance training: A systematic review and meta-analysis. Sports Medicine, 45(2), 245255. PubMed ID: 25355074 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Forrest, K.Y.Z., Zmuda, J.M., & Cauley, J.A. (2007). Patterns and correlates of muscle strength loss in older women. Gerontology, 53(3), 140147. PubMed ID: 17167267 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Galbreath, M., Campbell, B., LaBounty, P., Bunn, J., Dove, J., Harvey, T., . . . Kreider, R.B. (2018). Effects of adherence to a higher protein diet on weight loss, markers of health, and functional capacity in older women participating in a resistance-based exercise program. Nutrients, 10(8), E1070. PubMed ID: 30103509 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Grimby, G., Danneskiold-Samsøe, B., Hvid, K., & Saltin, B. (1982). Morphology and enzymatic capacity in arm and leg muscles in 78–81 year old men and women. Acta Physiologica Scandinavica, 115(1), 125134. PubMed ID: 7136797 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Hayes, A., & Cribb, P.J. (2008). Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training. Current Opinion in Clinical Nutrition and Metabolic Care, 11(1), 4044. PubMed ID: 18090657 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Henwood, T.R., & Taaffe, D.R. (2006). Short-term resistance training and the older adult: The effect of varied programmes for the enhancement of muscle strength and functional performance. Clinical Physiology and Functional Imaging, 26(5), 305313. PubMed ID: 16939509 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Iannuzzi-Sucich, M., Prestwood, K.M., & Kenny, A.M. (2002). Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. The Journals of Gerontology, Series A: Biological Sciences & Medical Sciences, 57(12), M772M777. PubMed ID: 12456735 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Katsanos, C.S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., & Wolfe, R.R. (2006). A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. American Journal of Physiology: Endocrinology and Metabolism, 291(2), E381E387. PubMed ID: 16507602 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kent-Braun, J.A., Ng, A.V., & Young, K. (2000). Skeletal muscle contractile and noncontractile components in young and older women and men. Journal of Applied Physiology, 88(2), 662668. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Keppel, G., & Wickens, T.D. (2004). Design and analysis: A researcher’s handbook (4th ed.). Upper Saddle River, NJ: Pearson Prentice Hall. Retrieved from https://trove.nla.gov.au/version/37029294

    • Search Google Scholar
    • Export Citation
  • Knuiman, P., van Loon, L.J.C., Wouters, J., Hopman, M., & Mensink, M. (2019). Protein supplementation elicits greater gains in maximal oxygen uptake capacity and stimulates lean mass accretion during prolonged endurance training: A double-blind randomized controlled trial. The American Journal of Clinical Nutrition, 110(2), 508518. PubMed ID: 31240303 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Landi, F., Camprubi-Robles, M., Bear, D.E., Cederholm, T., Malafarina, V., Welch, A.A., & Cruz-Jentoft, A.J. (2019). Muscle loss: The new malnutrition challenge in clinical practice. Clinical Nutrition, 38(5), 21132120. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Liao, C.-D., Lee, P.-H., Hsiao, D.-J., Huang, S.-W., Tsauo, J.-Y., Chen, H.-C., & Liou, T.-H. (2018). Effects of protein supplementation combined with exercise intervention on frailty indices, body composition, and physical function in frail older adults. Nutrients, 10(12), E1916. PubMed ID: 30518122 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Liao, C.-D., Tsauo, J.-Y., Wu, Y.-T., Cheng, C.-P., Chen, H.-C., Huang, Y.-C., . . . Liou, T.-H. (2017). Effects of protein supplementation combined with resistance exercise on body composition and physical function in older adults: A systematic review and meta-analysis. The American Journal of Clinical Nutrition, 106(4), 10781091. PubMed ID: 28814401 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Markofski, M.M., Jennings, K., Timmerman, K.L., Dickinson, J.M., Fry, C.S., Borack, M.S., . . . Volpi, E. (2019). Effect of aerobic exercise training and essential amino acid supplementation for 24 weeks on physical function, body composition, and muscle metabolism in healthy, independent older adults: A randomized clinical trial. The Journals of Gerontology, Series A: Biological Sciences & Medical Sciences, 74(10), 15981604. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Martin, K.A., & Sinden, A.R. (2001). Who will stay and who will go? A review of older adults’ adherence to randomized controlled trials of exercise. Journal of Aging and Physical Activity, 9(2), 91114. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Mitchell, W.K., Williams, J., Atherton, P., Larvin, M., Lund, J., & Narici, M. (2012). Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; A quantitative review. Frontiers in Physiology, 3, Article 260. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Moher, D., Hopewell, S., Schulz, K.F., Montori, V., Gotzsche, P.C., Devereaux, P.J., . . . Altman, D.G. (2010). CONSORT 2010 explanation and elaboration: Updated guidelines for reporting parallel group randomised trials. British Medical Journal, 340, c869. PubMed ID: 20332511 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Nicklas, B.J., Chmelo, E., Delbono, O., Carr, J.J., Lyles, M.F., & Marsh, A.P. (2015). Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: A randomized controlled trial. The American Journal of Clinical Nutrition, 101(5), 991999. PubMed ID: 25762810 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Paddon-Jones, D., Sheffield-Moore, M., Katsanos, C.S., Zhang, X.-J., & Wolfe, R.R. (2006). Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Experimental Gerontology, 41(2), 215219. PubMed ID: 16310330 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Rieu, I., Balage, M., Sornet, C., Giraudet, C., Pujos, E., Grizard, J., . . . Dardevet, D. (2006). Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. The Journal of Physiology, 575(Pt 1), 305315. PubMed ID: 16777941 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Rolland, Y., Czerwinski, S., Abellan Van Kan, G., Morley, J.E., Cesari, M., Onder, G., . . . Vellas, B. (2008). Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives. The Journal of Nutrition, Health & Aging, 12(7), 433450. PubMed ID: 18615225 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sayer, A.A., Syddall, H.E., Martin, H.J., Dennison, E.M., Roberts, H.C., & Cooper, C. (2006). Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study. Age and Ageing, 35(4), 409415. PubMed ID: 16690636 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Shafiee, G., Keshtkar, A., Soltani, A., Ahadi, Z., Larijani, B., & Heshmat, R. (2017). Prevalence of sarcopenia in the world: A systematic review and meta-analysis of general population studies. Journal of Diabetes and Metabolic Disorders, 16(1), 21. PubMed ID: 28523252 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sillanpää, E., Häkkinen, K., Holviala, J., & Häkkinen, A. (2012). Combined strength and endurance training improves health-related quality of life in healthy middle-aged and older adults. International Journal of Sports Medicine, 33(12), 981986. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Timmerman, K.L., Dhanani, S., Glynn, E.L., Fry, C.S., Drummond, M.J., Jennings, K., . . . Volpi, E. (2012). A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults. The American Journal of Clinical Nutrition, 95(6), 14031412. PubMed ID: 22572647 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • van Uffelen, J.G.Z., Khan, A., & Burton, N.W. (2017). Gender differences in physical activity motivators and context preferences: A population-based study in people in their sixties. BMC Public Health, 17(1), 624. PubMed ID: 28676081 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Volpi, E., Sheffield-Moore, M., Rasmussen, B.B., & Wolfe, R.R. (2001). Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. The Journal of the American Medical Association, 286(10), 12061212. PubMed ID: 11559266 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Yoshiko, A., Tomita, A., Ando, R., Ogawa, M., Kondo, S., Saito, A., . . . Akima, H. (2018). Effects of 10-week walking and walking with home-based resistance training on muscle quality, muscle size, and physical functional tests in healthy older individuals. European Review of Aging and Physical Activity, 15(1), 13. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
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