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Background: The authors tested the efficacy of the “I-STAND” intervention for reducing sitting time, a novel and potentially health-promoting approach, in older adults with obesity. Methods: The authors recruited 60 people (mean age = 68 ± 4.9 years, 68% female, 86% White; mean body mass index = 35.4). The participants were randomized to receive the I-STAND sitting reduction intervention (n = 29) or healthy living control group (n = 31) for 12 weeks. At baseline and at 12 weeks, the participants wore activPAL devices to assess sitting time (primary outcome). Secondary outcomes included fasting glucose, blood pressure, and weight. Linear regression models assessed between-group differences in the outcomes. Results: The I-STAND participants significantly reduced their sitting time compared with the controls (–58 min per day; 95% confidence interval [–100.3, –15.6]; p = .007). There were no statistically significant changes in the secondary outcomes. Conclusion: I-STAND was efficacious in reducing sitting time, but not in changing health outcomes in older adults with obesity.

Rosenberg, Anderson, Renz, Matson, Lee, Greenwood-Hickman, Arterburn, and McClure are with the Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA. Gardiner is with the Centre for Health Services Research, The University of Queensland, Brisbane, Queensland, Australia. Kerr is with The Grant Doctor, San Diego, CA, USA.

Rosenberg (Dori.E.Rosenberg@kp.org) is corresponding author.
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