The purpose of our quasi-experimental study was to examine the impact of the Girls on the Run (GOTR) program on multidimensional self-concept and attitudes toward fat. Young girls (N= 21) participated in a 12-week running program designed to increase their running ability, self-esteem, and, in general, their emotional, social, and mental well-being. It was hypothesized that girls would experience favorable changes in their global self-esteem, appearance, peer, physical, and running self-concepts and their attitudes toward fat. The overall RM-ANOVA examining for pre to post differences was significant, F(13, 8) = 26.46, p < .001, η2 = .977, and follow-up within subjects contrasts revealed three significant differences: Physical, F(1, 20) = 6.24, p < .02, η2 = .24, and running self-concept, F(1, 20) = 11.18, p< .003, η2 = .36, as well as fear of fat, F(1, 20) = 4.37, p < .049, η2 = .18, were all significant with meaningful effect sizes. These findings provided preliminary support for the major goal of the GOTR program, enhancing physical and running self-concept with some support for secondary gains in nonphysical ability areas (i.e., reductions in fear of fat).