Recent technological advances allow for field-based data collection of accelerometers in community-based studies. Mail-based administration can markedly reduce the cost and logistic challenges and burden associated with in-person data collection. It necessitates, however, other resources, such as phone calls and mailed reminder prompts, to increase protocol compliance and data recovery. Additionally, lost accelerometers can impact the study’s budget and its internal validity due to missing data. In this article, we present an applied methodological approach used to define thresholds (or cutoff points) at which pursuing unreturned accelerometers is a worthwhile versus futile pursuit. This methodological approach was designed, specifically, to maximize scalability across multiple sectors. We used data from an on-going study that administered accelerometers through the mail to illustrate and encourage investigators to replicate the approach for use in their own studies. In heterogeneous study samples, investigators might consider repeating this approach by study-relevant strata to refine thresholds and improve the return percentages of data collection instruments, minimize the potential missing data, and optimize study staff time and resources.