Restricted access


Physical activity (PA) may play a role in preserving kidney health. The purpose of this study was to determine if PA and sedentary behavior are associated with incident chronic kidney disease (CKD) and change in kidney function in older adults.


The Health, Aging, and Body Composition study is a prospective cohort of 3075 well-functioning older adults. PA and television watching was measured by self-report, and serum cystatin C was used to estimate glomerular filtration rate (eGFR). CKD was defined as an eGFR <60 ml/min/1.73m2. Rapid kidney function decline was defined as an annual loss in eGFR of >3ml/min/1.73m2. Discrete survival analysis was used to determine if baseline PA and television watching were related to 10-year cumulative incidence of CKD and rapid decline in kidney function.


Individuals who reported watching television >3 hours/day had a higher risk of incident CKD (HR 1.34; 95% CI, 1.09-1.65) and experiencing a rapid decline in kidney function (HR 1.26; 95% CI, 1.05-1.52) compared with individuals who watched television <2 hours/day. PA was not related to either outcome.


High levels of television watching are associated with declining kidney function; the mechanisms that underlie this association need further study.

Hawkins ( and Fried are with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts–Amherst, Amherst, MA. Fried is also with the VA Pittsburgh Healthcare System, Pittsburgh, PA. Newman and Cooper are with the Dept of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. Madero is with the Instituto Nacional de Cardiología Ignacio Chávez, México City, México. Patel is with the Dept of Anesthesiology & Pain Medicine, University of Washington, Seattle, WA. Shlipak and Johansen are with the San Francisco VA and Dept of Medicine, University of California, San Francisco, San Francisco, CA. Navaneethan is with the Dept of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH. Shorr is with the Dept of Epidemiology, University of Florida, Gainseville, FL. Simonsick is with the National Institute on Aging, Baltimore, MD.