The Effect of Cardiac Rehabilitation in Men With and Without Prostate Cancer: A Retrospective, Comparative Cohort Study

in Journal of Physical Activity and Health
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Background: Men with prostate cancer (PCa) may be referred to cardiac rehabilitation (CR) following a significant cardiac event, but it is unknown if these men have different effects of CR from men without a history of PCa. Purpose: To compare the effect of CR on cardiorespiratory fitness (VO2peak), body fat percentage, and body mass index in men with and without a history of PCa. Methods: CR participants with PCa were retrospectively compared with a cohort matched on age, clinical indication for CR, and date of referral to the CR program. Participants completed the standardized CR program at the Toronto Rehabilitation Institute, including 1 weekly supervised group session and 4 additional weekly home sessions including aerobic and resistance training for 26 weeks. Results: Twenty-seven (n = 27) men with PCa were identified and matched 1∶1 with controls. VO2peak increased in the PCa group (16.9 [5.1]–19.6 [6.2] mL·kg−1·min−1; Δ 2.7 mL·kg−1·min−1, P < .05) and in the control group (16.4 [4.2]–20.2 [5.8] mL·kg−1·min−1; Δ 3.8 mL·kg−1·min−1, P < .05) as a result of engaging in CR. There were no significant between-group differences in the postintervention outcomes (P > .05). Conclusions: Men with and without PCa experience comparable benefits following CR completion.

Bonsignore, Field, Dolan, and Oh are with Cardiovascular Prevention and Rehabilitation Program, Toronto Rehabilitation Institute, Toronto, ON, Canada. Bonsignore and Santa Mina are with the Faculty of Kinesiology & Physical Education, University of Toronto, Toronto, ON, Canada. Speare is with the Faculty of Kinesiology, University of Guelph-Humber, Toronto, ON, Canada. Santa Mina is also with Cancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.

Santa Mina (daniel.santamina@utoronto.ca) is corresponding author.
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