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The postgenomic era and heightened public expectations for tangible improvements in the public health have stimulated a complete transformation of the nation's biomedical research enterprise. The National Institutes of Health (NIH) “Roadmap for Medical Research” has catalyzed this transformation. The NIH roadmap consists of several interrelated initiatives, of which the Clinical and Translational Science Award (CTSA) program is the most relevant for rehabilitation specialists. This article reviews the evolution of this transformation and highlights the unprecedented opportunities the CTSA program provides rehabilitation specialists to play leadership roles in improving the clinical care of their patients.
Balke is with the Clinical and Translational Science Institute, University of California, San Francisco, San Francisco, CA. Umberger is with the Patient Quality and Safety Program, Lexington VA Medical Center, Lexington, KY. Mattacola is with the Div of Athletic Training, University of Kentucky, Lexington, KY.