Osteochondral defects are often symptomatic and lead to deranged joint function. The spontaneous healing capacity of osteochondral defects is limited. In this case study, use of an acellular scaffold capable of induction of mesenchymal stem-cell migration is described. This scaffold was used on an Outerbridge grade IV medical condylar defect measuring ~2 cm2. At 24 mo follow-up, the articular surface appeared restored by MRI, and the patient returned to sports.
Kon is with III Clinic—Biomechanics Laboratory, Rizzoli Orthopaedic Inst, Bologna, Italy. Drobnic is with the Dept of Orthopedics, University of Ljubliana, Ljubliana, Slovenia. Davidson is with Heiden Davidson Orthopedics, Park City, UT. Levy is with the Center for Advanced Sports Medicine Knee and Shoulder, Morristown, NJ. Zaslav is with the Dept of Orthopedic Surgery, Virginia Commonwealth University, Richmond, VA. Robinson is with the Orthopedic Research & Foot and Ankle Unit, Sackler School of Medicine, Rabin Medical Center, Petah Tikwa, Israel. Address author correspondence to Dror Robinson at firstname.lastname@example.org.