The Effect of Blood Flow Restriction on Muscle Hypertrophy and Tendon Thickness in Healthy Adults’ Distal Lower-Extremity: A Critically Appraised Topic

in Journal of Sport Rehabilitation
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Post, Stackhouse, Ostrowski, and Payne are with Moravian University, Bethlehem, PA, USA. Bettleyon is with Methodist University, Fayetteville, NC, USA.

Payne (paynee@moravian.edu) is corresponding author.
  • 1.

    Lambert BS, Hedt C, Moreno M, Harris JD, McCulloch P. Blood flow restriction therapy for stimulating skeletal muscle growth: practical considerations for maximizing recovery in clinical rehabilitation settings. Techniques in Ortho. 2018;33(2):8997. doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Giles L, Webster KE, McClelland J, Cook JL. Quadriceps strengthening with and without blood flow restriction in the treatment of patellofemoral pain: a double-blind randomised trial. Br J Sports Med. 2017;51(23):16881694. PubMed ID: 28500081 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3.

    Takarada Y, Tsuruta T, Ishii N. Cooperative effects of exercise and occlusive stimuli on muscular function in low-intensity resistance exercise with moderate vascular occlusion. Jpn J Physiol. 2004;54(6):585592. PubMed ID: 15760491 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    Abe T, Fujita S, Nakajima T. Effects of low-intensity cycle training with restricted leg blood flow on thigh muscle volume and VO2max in young men. J Sports Sci Med. 2010;9(3):452458. PubMed ID: 24149640

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Ozaki H, Sakamaki M, Yasuda T. Increases in thigh muscle volume and strength by walk training with leg blood flow reduction in older participants. J Gerontol A Biol Sci Med Sci. 2011;66(3):257263. PubMed ID: 20974731 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    Segal N, Davis MD, Mikesky AE. Efficacy of blood flow-restricted low-load resistance training for quadriceps strengthening in men at risk of symptomatic knee osteoarthritis. Geriatr Orthop Surg Rehabil. 2015;6(3):160167. PubMed ID: 26328230 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    Takarada Y, Takazawa H, Ishii N. Applications of vascular occlusion diminish disuse atrophy of knee extensor muscles. Med Sci Sports Exerc. 2000;32(12):20352039. PubMed ID: 11128848 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Dankel SJ, Jessee MB, Abe T, Loenneke JP. The effects of blood flow restriction on upper-body musculature located distal and proximal to applied pressure. Sports Med. 2016;46(1):2333. PubMed ID: 26446893 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    Burgomaster KA, Moore DR, Schofield LM, Phillips SM, Sale DG, Gibala MJ. Resistance training with vascular occlusion: metabolic adaptations in human muscle. Med Sci Sports Exerc. 2003;35(7):12031208. PubMed ID: 12840643 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Yasuda T, Loenneke JP, Ogasawara R, Abe T. Influence of continuous or intermittent blood flow restriction on muscle activation during low-intensity multiple sets of resistance exercise. Acta Physiol Hung. 2013;100(4):419426. PubMed ID: 24317348 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55(2):129133. PubMed ID: 19463084 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    Centner C, Lauber B, Seynnes OR. Low-load blood flow restriction training induces similar morphological and mechanical Achilles tendon adaptations compared with high-load resistance training. J Appl Physiol. 2019;127(6):16601667. doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13.

    Colomer-Poveda D, Romero-Arenas S, Vera-Ibáñez A, Viñuela-García M, Márquez G. Effects of 4 weeks of low-load unilateral resistance training, with and without blood flow restriction, on strength, thickness, v wave, and h reflex of the soleus muscle in men. Eur J Appl Physiol. 2017;117(7):13391347. PubMed ID: 28451748 doi:

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14.

    Gavanda S, Isenmann E, Schlöder Y, et al. Low-intensity blood flow restriction calf muscle training leads to similar functional and structural adaptations than conventional low-load strength training: a randomized controlled trial. PLoS One. 2020;15(6):e0235377. doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    Chulvi-Medrano I, Picón-Martínez M, Cortell-Tormo JM, Tortosa-Martínez J, Alonso-Aubin DA, Alakhdar Y. Different time course of recovery in Achilles tendon thickness after low-load resistance training with and without blood flow restriction. J Sport Rehabil. 2020;30(2):300305. doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Slysz J, Stultz J, Burr JF. The efficacy of blood flow restricted exercise: a systematic review & meta-analysis. J Sci Med Sport. 2016;19(8):669675. PubMed ID: 26463594 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    Ferraz RB, Gualano B, Rodrigues R, et al. Benefits of resistance training with blood flow restriction in knee osteoarthritis. Med Sci Sports Exerc. 2018;50(5):897905. PubMed ID: 29266093 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18.

    SmartCuffs® PRO. SmartCuffs® PRO | Smart Tools. https://www.smarttoolsplus.com/detail.cfm/id/400/name/smartcuffs-pro?gclid=Cj0KCQjwxNT8BRD9ARIsAJ8S5xZDcjQ0izSMZpT6FPfmuDDPqJ6gT93hszkfYNwY2vyI9dAMVfJqaqkaApIXEALw_wcB. Accessed October 25, 2020.

    • Search Google Scholar
    • Export Citation
  • 19.

    Patterson SD, Hughes L, Warmington S, et al. Blood flow restriction exercise: considerations of methodology, application, and safety. Front Physiol. 2019;10:533. PubMed ID: 31156448 doi:.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20.

    Silva JCG, Pereira Neto EA, Pfeiffer PAS, et al. Acute and chronic responses of aerobic exercise with blood flow restriction: a systematic review. Front Physiol. 2019;10:1239. PubMed ID: 31636569 doi:

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
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