Context: Running is a popular form of physical activity but can increase an individual’s lower-extremity injury risk. Running gait analysis via inertial measurement units (IMUs) is a method for collecting important gait data that is related to developing lower-extremity injuries, such as increased load from low step rate (SR), and long stride length (SL). IMU data can be derived from both foot- and shank-placed IMUs, but foot-placed sensors (RunScribe IMUs) need validation against shank-placed sensors. Purpose: Determine criterion validity of RunScribe foot-placed IMUs against MyoMotion shank-placed IMU for SR and SL. Design: cross-sectional laboratory study. Methods: Nine participants (5 males, 4 females; age: 28.33 [5.78]; height: 1.75 [0.11]; mass: 74.06 [16.24]) volunteered for our study. Following a 5-minute warm-up, participants ran on a treadmill for 5 minutes at a self-selected speed. After ∼2.5 minutes, MyoMotion data were collected for 10 seconds. The RunScribe IMUs collected data throughout the full duration of the run. Criterion validity of SR and SL between the foot- and shank-placed IMUs was determined using bivariate Pearson correlations, intraclass correlation coefficients (3,1), and Bland–Altman plots with 95% limits of agreement analysis. Results: A very strong correlation for SR (r = .90, N = 9, P ≤ .001), and a strong correlation for SL (r = .80, N = 9, P < .001) were found between the foot and shank-placed IMUs. Excellent reliability was found for SR (intraclass correlation coefficient = .91, P ≤ .001, 95% CI, .639–.978), and good reliability was found for SL (intraclass correlation coefficient = .800, P = .003, 95% CI, .340–.951) between the foot and shank-placed IMUs. The mean difference of SR and SL was −2.111 and −0.142, respectively, indicating good agreement between the foot and shank-placed IMUs. Conclusions: Foot-placed RunScribe IMUs are a valid alternative for measuring SR and SL compared with shank-placed IMUs.