We investigated whether children with suspected Developmental Coordination Disorder (DCD⁺) demonstrate different physical fitness levels compared with their normal peers (DCD⁻). Randomly recruited Greek children (n = 177) were assessed for body mass index (BMI), flexibility (SR), vertical jump (VJ), hand strength (HS), 40m dash, aerobic power, and motor proficiency. ANCOVA revealed a motor proficiency (i.e., DCD group) effect for BMI (p < .01), VJ (p < .01), and 40m speed (p < .01), with DCD⁺ children demonstrating lower values than DCD⁻. Differences between DCD⁺ and DCD⁻ were also obtained in log-transformed HS (p < .01). These findings suggest that intervention strategies for managing DCD should also aim at physical fitness increases.