ACE I/D Genotype, Habitual Physical Activity, and Blood Pressure in Children

in Pediatric Exercise Science
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The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p < .05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.

Sarzynski and Eisenmann are with the Depts. of Kinesiology and Pediatrics and Human Development, Michigan State University, East Lansing, MI. Welk and Tucker are with the Dept. of Kinesiology, Iowa State University, Ames, IA. Glenn and Rothschild are with the Dept. of Animal Science, Iowa State University, Ames, IA. Heelan is with the Dept. of Kinesiology, University of Nebraska-Kearney, Kearney, NE.