Adipocytokine Levels in Children: Effects of Fatness and Training

in Pediatric Exercise Science
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  • 1 University of Thessaly
  • 2 Institute of Human Performance and Rehabilitation
  • 3 University of Botswana
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To investigate the effects of obesity and exercise training on plasma adipocytokines a sample of 42 children (lean = 24, %BF = 17.8 ± 7.5%; obese = 18; %BF = 29.1 ± 9.3%; mean age = 12.4 ± 1.9 yrs), were divided into 4 age-matched for activity groups: lean inactive (n = 11), obese inactive (n = 9), lean active (n = 13) and obese active (n = 9). Active children participated in swimming training (≥1 year, ≥3 times/week, ≥1 h per session, covering a distance of 10,000−12,000 m per week). Obese individuals demonstrated greater visfatin levels (3.3 ± 1.3 ng/ml) than their lean counterparts (2.6 ± 1.1 ng/ml; p = .06) whereas adiponectin was significantly lower in obese children (3.8 ± 1.9) than their lean counterparts (5.9 ± 2.7; p £ .05). Insulin and HOMA values were significantly greater in obese compared with lean children (p £ .05). Within obese individuals, active individuals had significantly lower visfatin levels (2.8 ± 1.2 ng/ml) compared with their inactive counterparts (3.8 ± 1.2 ng/ml; p £ .05). Resistin levels were comparable between groups (p > .05). Childhood obesity elevates visfatin and lowers adiponectin levels whereas exercise training could reduce visfatin levels in obese children.

Aggeloussi, Theodorou, Paschalis, Nikolaidis, Fatouros, Owolabi, Kouretas, Koutedakis, and Jamurtas are with the Dept. of Physical Education and Sport Science, University of Thessaly, Karies, Trikala, Greece. Aggeloussi and Fatouros are with the Dept. of Physical Education and Sport Science, University of Thrace, Komotini, Greece. Theodorou, Paschalis, Nikolaidis, Koutedakis, and Jamurtas are with the Institute of Human Performance and Rehabilitation, Centre for Research and Technology, Thessaly, Greece. Nikolaidis is with the Dept. of Physical Education and Sport Science, Aristotle University of Thessaloniki, Greece. Owolabi is with the Dept. of Physical Education Health and Recreation, University of Botswana, Gaborone, Botswana. Kouretas is with the Dept of Biochemistry and Biotechnology, University of Thessaly, Greece. Koutedakis is with the School of Sports, Performing Arts and Leisure, University of Wolverhampton, UK.