This essay introduces interpersonal exploitation in Black women’s relationships in U.S. Division I college athletic environments. Interpersonal exploitation is a Black feminist-oriented analytical frame for exploring how relationships across various levels and systems contribute to the exploitation of Black women and other similarly situated populations in U.S. college athletics. Drawing from existing research, this essay describes how and why scholars, policymakers, and practitioners can use this analytical frame to explore how relationships, and systems that inform these relationships, sustain conditions in which athletes and professionals can be systematically exploited. Addressing exploitation is vital to restore college athletics’ integrity, emphasizing its educational role, and prioritizing well-being.