lactate. 1 Extracellular buffering mechanisms act to remove these H + from the skeletal muscle cell, but once production rates overwhelm neutralization reactions, the excess H + contribute toward decreasing intramuscular pH. 2 Exercise-induced acidosis inhibits glycolytic energy production and
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William H. Gurton, Steve H. Faulkner, and Ruth M. James
Alannah K.A. McKay, Peter Peeling, Martyn J. Binnie, Paul S.R. Goods, Marc Sim, Rebecca Cross, and Jason Siegler
The ingestion of sodium bicarbonate (NaHCO 3 ) is well accepted as an efficacious ergogenic aid to improve short-duration, high-intensity exercise performance. 1 The exogenous intake of NaHCO 3 acts as an extracellular buffer, raising blood pH and bicarbonate (HCO 3 − ) concentrations and
Jason C. Siegler, Amelia J. Carr, William T. Jardine, Lilia Convit, Rebecca Cross, Dale Chapman, Louise M. Burke, and Megan Ross
influencing the individual responses to extracellular buffering agents . Frontiers in Nutrition, 5, 35 . https://doi.org/10.3389/fnut.2018.00035 10.3389/fnut.2018.00035 Kowalchuk , J.M. , Maltais , S.A. , Yamaji , K. , & Hughson , R.L. ( 1989 ). The effect of citrate loading on exercise
Charles S. Urwin, Rodney J. Snow, Dominique Condo, Rhiannon M.J. Snipe, Glenn D. Wadley, Lilia Convit, and Amelia J. Carr
, 44 ( Suppl. 1 ), 79 – 85 . https://doi.org/10.1007/s40279-014-0153-2 10.1007/s40279-014-0153-2 de Oliveira , L.F. , Dolan , E. , Swinton , P.A. , Durkalec-Michalski , K. , Artioli , G.G. , McNaughton , L.R. , & Saunders , B. ( 2021 ). Extracellular buffering supplements to improve
Tue A.H. Lassen, Lars Lindstrøm, Simon Lønbro, and Klavs Madsen
al., 2004 ) and in line with the suggested effect for SBS in improving extracellular buffering and subsequently increasing intramuscular pH during the exercise period ( Hargreaves & Spriet, 2020 ). In order to investigate the effect of SBS on performance, one needs to consider the large individual variation
Rodrigo dos Santos Guimarães, Alcides Correa de Morais Junior, Raquel Machado Schincaglia, Bryan Saunders, Gustavo Duarte Pimentel, and João Felipe Mota
, P.H.L. , Oliveira , L.F. , McNaughton , L.R. , & Saunders , B. ( 2018 ). Time to optimize supplementation: modifying factors influencing the individual responses to extracellular buffering agents . Frontiers in Nutrition, 5 ( 5 ), 35 . PubMed ID: 29868599 doi:10.3389/fnut.2018.00035 10
Rebecca L. Jones, Trent Stellingwerff, Paul Swinton, Guilherme Giannini Artioli, Bryan Saunders, and Craig Sale
.R. , & Saunders , B. ( 2018 ). Time to optimize supplementation: Modifying factors influencing the individual responses to extracellular buffering agents . Frontiers in Nutrition, 5, 35 . https://doi.org/10.3389/fnut.2018.00035 10.3389/fnut.2018.00035 Ingham , S.A. , Fudge , B.W. , Pringle , J
Charles S. Urwin, Rodney J. Snow, Dominique Condo, Rhiannon Snipe, Glenn D. Wadley, and Amelia J. Carr
factors influencing the individual responses to extracellular buffering agents . Frontiers in Nutrition, 5 ( 1 ), 35 . PubMed ID: 29868599 doi:10.3389/fnut.2018.00035 10.3389/fnut.2018.00035 Hilton , N. , Leach , N. , Sparks , A. , Gough , L. , Craig , M. , Deb , S. , & McNaughton , L
Ricardo Augusto Silva de Souza, André Guedes da Silva, Magda Ferreira de Souza, Liliana Kataryne Ferreira Souza, Hamilton Roschel, Sandro Fernandes da Silva, and Bryan Saunders
.2017-0273 Heibel , A.B. , Perim , P.H.L. , Oliveira , L.F. , McNaughton , L.R. , & Saunders , B. ( 2018 ). Time to optimize supplementation: Modifying factors influencing the individual responses to extracellular buffering agents . Frontiers in Nutrition, 5, 35 . PubMed ID: 29868599 doi
Graeme L. Close, Andreas M. Kasper, Neil P. Walsh, and Ronald J. Maughan
, 18 . https://doi.org/10.1186/s12970-017-0173-z 10.1186/s12970-017-0173-z Lancha Junior , A.H. , de Salles Painelli , V. , Saunders , B. , & Artioli , G.G. ( 2015 ). Nutritional strategies to modulate intracellular and extracellular buffering capacity during high-intensity exercise . Sports
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