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Open access

The Effect of 1,3-Butanediol on Cycling Time-Trial Performance

David M. Shaw, Fabrice Merien, Andrea Braakhuis, Daniel Plews, Paul Laursen, and Deborah K. Dulson

. , Ashmore , T. , Willerton , K. , Evans , R. , Smith , A. , . . . Clarke , K. ( 2016 ). Nutritional ketosis alters fuel preference and thereby endurance performance in athletes . Cell Metabolism, 24 ( 2 ), 256 – 268 . PubMed ID: 27475046 doi:10.1016/j.cmet.2016.07.010 10.1016/j.cmet.2016

Open access

Acute Ingestion of Ketone Monoesters and Precursors Do Not Enhance Endurance Exercise Performance: A Systematic Review and Meta-Analysis

Emma Brooks, Gilles Lamothe, Taniya S. Nagpal, Pascal Imbeault, Kristi Adamo, Jameel Kara, and Éric Doucet

) diet ( Cox & Clarke, 2014 ; Robinson & Williamson, 1980 ). Under all of these circumstances, KBs become a pertinent energy source while glucose is restricted or depleted. Ketosis, or hyperketonaemia, is defined as plasma ketone concentrations that exceed 0.2 mM, according to Robinson and Williamson

Free access

Effects of Ketone Monoester and Bicarbonate Co-Ingestion on Cycling Performance in WorldTour Cyclists

Domingo Jesús Ramos-Campo, Francisco Javier López-Román, Silvia Pérez-Piñero, Raquel Ortolano, María Salud Abellán-Ruiz, Enrique Molina Pérez de los Cobos, Antonio Jesús Luque-Rubia, Dag Van Elslande, and Vicente Ávila-Gandía

and the heart, with greater contribution observed in exogenous ketosis ( Evans et al., 2017 ). Hyperketonemia is defined as a plasma ketone concentration above 0.5 mM ( Robinson & Williamson, 1980 ). β-Hydroxybutyrate (βHB) is the most common circulating ketone body, and exogenous ketones are often

Open access

Gastrointestinal Effects of Exogenous Ketone Drinks are Infrequent, Mild, and Vary According to Ketone Compound and Dose

Brianna J. Stubbs, Pete J. Cox, Tom Kirk, Rhys D. Evans, and Kieran Clarke

ketone drinks has grown ( Egan & D’Agostino, 2016 ). These drinks rapidly increase blood ketone concentrations to achieve ketosis (blood d -βHB >0.5 mM) without dietary modification ( Stubbs et al., 2017 ). Two classes of exogenous ketone compounds exist: ketone esters and ketone salts (KS). Ketone

Open access

A Framework for Periodized Nutrition for Athletics

Trent Stellingwerff, James P. Morton, and Louise M. Burke

% energy from CHO to prevent ketosis while reducing CHO intake to levels below the fuel costs of daily training) and the more restrictive ketogenic LCHF diet (K-LCHF: typically <50 g/day CHO and 75–80% fat; Burke et al., 2018 ). However, studies have shown that as little as 5 days of exposure to HFLC

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SPRINTING. . . Dietary Approaches to Optimize Training Adaptation and Performance

Gary J. Slater, Jennifer Sygo, and Majke Jorgensen

only following severe dietary carbohydrate restriction, sufficient to promote a state of ketosis. Such a state is unlikely among competitive athletes tapering prior to competition who follow a meal plan with even a moderate carbohydrate content. In light of this, sprint athletes are advised to choose a

Open access

Abstracts From the December 2019 International Sport + Exercise Nutrition Conference in Newscastle upon Tyne

), incorporating MCT into the diet may allow more carbohydrates yet preserving ketosis and exert less inhibitory effect on muscle glucose metabolism. The purpose of this study was therefore to examine the effects of long-term feeding of ketogenic diet containing MCT on key metabolic enzymes in rat skeletal muscle

Open access

Ketone Monoester Ingestion Alters Metabolism and Simulated Rugby Performance in Professional Players

Oliver J. Peacock, Javier T. Gonzalez, Simon P. Roberts, Alan Smith, Scott Drawer, and Keith A. Stokes

and both made an estimated 16  kJ/kg body mass (BM) available for metabolism (total energy intake 1,528 ± 145 kJ). The ketone monoester was provided at a total dose of 590 mg/kg BM based on pilot data showing that this dosing level induces a sustained moderate ketosis (blood BHB of ∼2–3 mmol/L) that

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Acute Ketone Monoester Supplementation Impairs 20-min Time-Trial Performance in Trained Cyclists: A Randomized, Crossover Trial

Devin G. McCarthy, Jack Bone, Matthew Fong, Phillippe J.M. Pinckaers, William Bostad, Douglas L. Richards, Luc J.C. van Loon, and Martin J. Gibala

Nutritional ketosis induced through the ingestion of ketogenic supplements can alter physiological responses to exercise ( Evans et al., 2017 ). This practice has also been purported to enhance performance, at least under selected conditions, although the precise mechanistic basis is unclear

Free access

Adherence to a Ketogenic Low-Carbohydrate, High-Fat Diet Is Associated With Diminished Training Quality in Elite Racewalkers

Alannah K.A. McKay, Megan L.R. Ross, Nicolin Tee, Avish P. Sharma, Jill J. Leckey, and Louise M. Burke

perceived exertion per kilometer travelled and a higher perceptual (RPE) and physiological (HR) effort for any given speed. The LCHF diet was associated with a sustained increase in concentrations of blood β HB concentrations above the level considered to signal ketosis (0.5 mM) 2 and within proposed