The purpose of this study was to provide an in-depth sports medicine profile of women college tennis players and determine the relationships among an array of performance and clinical variables. Thirty-eight non-resistance-trained women from NCAA Divisions I and III collegiate tennis teams participated. A comprehensive battery of performance tests was conducted on each subject, including measurements of dynamic, isometric, and isokinetic strength; joint laxity and flexibility; speed; agility; power and power endurance; peak oxygen consumption; body composition; and ball velocities of the serve, forehand, and backhand. It was found that no single variable strongly explains tennis performance. The low amount of shared variance of strength measures with ball velocities suggests that tennis skills play a large role in producing peak ball velocities in this group. Due to the large range observed in profiled variables, individual evaluation is needed for clinical and conditioning recommendations.