Background: People with Parkinson’s disease (PD) present cognitive impairments, which deteriorate their quality of life and increase disability. Acute aerobic exercise has demonstrated favorable effects on cognitive function in healthy neurologically individuals, but these effects have a dose–response relationship. Therefore, this study aimed to investigate the acute effects of high-intensity interval training (HIIT) versus continuous moderate-intensity training (MICT) on cognitive functions in people with PD. Methods: A total of 14 individuals with PD performed cognitive tests, before and after 3 sessions—control session (CON), HIIT, and MICT. HIIT and MICT were performed on a stationary bicycle. HIIT consisted of a 25-minute exercise of high-intensity intervals (1 min) alternated with moderate-intensity intervals (2 min). MICT consisted of a 30-minute moderate-intensity exercise. CON was 30 minutes of seated resting. The cognitive parameters were compared by a mixed-model analysis for repeated measures. Results: Acute effects of exercise were according to its type: MICT—improved immediate auditory memory (P < .01); HIIT—improved immediate auditory memory (P < .02), attention (P < .001), and sustained attention (P < .01); and CON—no effects on cognitive function. Conclusions: Acute aerobic exercise was able to promote better cognitive performance in people with PD. The effects on cognition were exercise intensity dependent.
Carolina Menezes Fiorelli, Emmanuel Gomes Ciolac, Lucas Simieli, Fabiana Araújo Silva, Bianca Fernandes, Gustavo Christofoletti and Fabio Augusto Barbieri
Bianca Fernandes, Fabio Augusto Barbieri, Fernanda Zane Arthuso, Fabiana Araújo Silva, Gabriel Felipe Moretto, Luis Felipe Itikawa Imaizumi, Awassi Yophiwa Ngomane, Guilherme Veiga Guimarães and Emmanuel Gomes Ciolac
Purpose: To investigate the effect of high-intensity interval training (HIIT) versus moderate-intensity continuous exercise training (MICE) on hemodynamic and functional variables in individuals with Parkinson’s disease. Methods: Twenty participants (13 men) were randomly assigned to a thrice-weekly HIIT (n = 12) or MICE (n = 8) for 12 weeks. Hemodynamic (resting heart rate and blood pressure, carotid femoral pulse wave velocity, endothelial reactivity, and heart rate variability) and functional variables (5-time sit-to-stand, timed up and go, and 6-min walking tests) assessed before and after training. Results: Demographic, hemodynamic and functional variables were similar between groups at baseline. Endothelial reactivity tended to increase after HIIT, but not after MICE, resulting in improved level (∼8%, P < .01) of this variable in HIIT versus MICE during follow-up. Six-minute walking test improved after HIIT (10.4 ± 3.8%, P < .05), but did not change after MICE. Sit to stand improved similarly after HIIT (27.2 ± 6.1%, P < .05) and MICE (21.5 ± 5.4%, P < .05). No significant changes were found after HIIT or MICE in any other variable assessed. Conclusion: These results suggest that exercise intensity may influence training-induced adaptation on endothelial reactivity and aerobic capacity in individuals with Parkinson’s disease.