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Yolanda Demetriou, Antje Hebestreit, Anne K. Reimers, Annegret Schlund, Claudia Niessner, Steffen Schmidt, Jonas David Finger, Michael Mutz, Klaus Völker, Lutz Vogt, Alexander Woll, and Jens Bucksch

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Annegret Schlund, Anne K. Reimers, Jens Bucksch, Catherina Brindley, Carolin Schulze, Lorri Puil, Stephanie E. Coen, Susan P. Phillips, Guido Knapp, and Yolanda Demetriou

Background: Physical inactivity is often reported in youth and differs among boys and girls. The aim of this study is to assess sex/gender considerations in intervention studies promoting physical activity and reducing sedentary behavior in youth using a sex/gender checklist. Methods: A systematic search was conducted in August 2018 to identify all relevant controlled trials. Studies screened must have reported a quantified measure of physical activity and/or sedentary behavior, and identified participants by sex/gender at baseline. For evaluation of the sex/gender consideration, the authors used a sex/gender checklist developed by expert consensus. Results: The authors reviewed sex/gender considerations in all aspects of intervention development, implementation, and evaluation in 217 studies. Sex/gender aspects were only rudimentarily taken into account, most frequently during statistical analyses, such as stratification or interaction analysis. Conclusions: Sex/gender effects are not sufficiently reported. To develop guidelines that are more inclusive of all girls and boys, future interventions need to document sex/gender differences and similarities, and explore whether sex/gender influences different phases of intervention programs. The newly developed sex/gender checklist can hereby be used as a tool and guidance to adequately consider sex/gender in the several steps of intervention planning, implementation, and evaluation.