Background: Skeletal muscle is overlooked in the realm of insulin resistance in children who are overweight and obese despite the fact that it accounts for the most glucose disposal. Objectives: Therefore, this study examined fasted glucose levels and muscle cross-sectional area and echo intensity (EI) via ultrasound images of the first dorsal interosseous, vastus lateralis, and rectus femoris in children who are normal weight and overweight and obese aged 8–10 years. Methods: In total, 13 males (age = 9.0 [0.7] y) and 7 females (age = 9.0 [0.8] y) volunteered for this study. Independent samples t tests and effect sizes (ESs) were used to examine potential differences in skeletal muscle composition and glucose concentrations. Results: There were no significant differences between groups for glucose concentration (P = .07, ES = 0.86); however, the children who were overweight and obese had significantly greater EI (P < .01, ES = 0.98–1.63) for the first dorsal interosseous, vastus lateralis, and rectus femoris and lower cross-sectional area when normalized to EI when collapsed across muscles (P < .04, ES = 0.92). Glucose concentrations correlated with EI and cross-sectional area/EI for the vastus lateralis (r = .514 to −.593) and rectus femoris (r = .551 to −.513), but not the first dorsal interosseous. Discussion: There is evidence that adiposity-related pathways leading to insulin resistance and skeletal muscle degradation are active in young children who are overweight and obese.
Trent J. Herda, Philip M. Gallagher, Jonathan D. Miller, Matthew P. Bubak, and Mandy E. Parra
Jonathan M. Miller, Mark A. Pereira, Julian Wolfson, Melissa N. Laska, Toben F. Nelson, and Dianne Neumark-Sztainer
Background: This study tested for differences in personal, social, and environmental correlates of moderate to vigorous physical activity (MVPA) across ethnicity/race in male and female adolescents. Methods: Self-reported MVPA and 47 potential correlates of MVPA were measured in an ethnically/racially diverse cross-sectional sample of adolescents, in Minnesota, who participated in EAT-2010 (Eating and Activity in Teens). Interactions of potential correlates with ethnicity/race on MVPA were tested in linear hierarchical regression models in boys and girls. Results: Boys reported 1.7 more weekly hours of MVPA than girls. White adolescents reported 1.1 to 2.1 more weekly hours of MVPA than nonwhite adolescents. Among girls, neighborhood road connectivity was negatively correlated with MVPA among Hispanic and Asian participants. Among boys, sports participation was positively correlated with MVPA among all ethnicities/races, except Asians. Home media equipment was positively correlated with MVPA among Hispanic boys, but negatively correlated among white boys. Conclusions: A few correlates of physical activity among adolescents differed intersectionally by ethnicity/race and sex. Sports participation and home media equipment may have differing impacts on physical activity across ethnicities and races in boys, whereas neighborhood features like road connectivity may have differing impacts on physical activity across ethnicities and races in girls.