Extending upon Iwasaki and Fry’s study published in 2016, the connections between mindfulness, goal orientations, and motivational climate perceptions were examined among exercisers. Participants (N = 324, 62% women) were surveyed six weeks into their group exercise classes on their perceptions of the class climate (caring, task-involving, and ego-involving), goal orientations (task and ego), and general mindfulness. Separate linear regressions for men and women were run to determine if exercisers’ perceptions of the motivational climate and their goal orientations predicted general mindfulness. Similar to previous research, ego goal orientation did not significantly predict mindfulness. In contrast to previous research, the regression model for women exercisers was not significant and predicted only 2.3% of general mindfulness variance. However, 9.6% of general mindfulness variance was predicted for men by the significant regression model. Men’s perceptions of the caring climate and their task goal orientation were similarly important positive predictors of mindfulness. By fostering a caring climate, exercise instructors have the potential to increase their participants’ general mindfulness, an important avenue for positively affecting participants’ quality of life.