Context: It is unclear if lower-extremity joint cooling alters biomechanics during a functional movement. Objective: To investigate the effects of unilateral lower-extremity cryotherapy on movement alterations during a single-leg drop jump. Design: A crossover design. Setting: Laboratory. Patients: Twenty healthy subjects (10 males and 10 females; 23 y, 169 cm, 66 kg). Intervention(s): Subjects completed a single-leg drop jump before and after a 20-minute ankle or knee joint cooling on the right leg, or control (seated without cooling) on 3 separate days. Main Outcome Measures: Time to peak knee flexion, vertical ground reaction force, lower-extremity joint angular velocity (sagittal plane only), and angle and moment (sagittal and frontal planes) in the involved leg over the entire ground contact (GC; from initial contact to jump-off) during the first landing. Time to peak knee flexion was compared using an analysis of variance; the rest of the outcome measures were analyzed using functional analyses of variance (P < .05). Results: Neither joint cooling condition changed the time to peak knee flexion (F 2,95 = 0.73, P = .49). Ankle joint cooling reduced vertical ground reaction force (55 N at 4% of GC), knee joint angular velocity (44°/s during 5%–9% of GC), and knee varus moment (181 N·m during 18%–20% of GC). Knee joint cooling resulted in a reduction in knee joint angular velocity (24°/s during 37%–40% of GC) and hip adduction moment (151 N·m during 46%–48% of GC), and an increase in hip joint angular velocity (16°/s during 49%–53% of GC) and plantarflexion angle (1.5° during 11%–29% of GC). Conclusion: Resuming activity immediately after lower-extremity joint cooling does not seem to predispose an individual to injury during landing because altered mechanics are neither overlapping with the injury time period nor of sufficient magnitude to lead to an injury.
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Single-Leg Drop Jump Biomechanics After Ankle or Knee Joint Cooling in Healthy Young Adults
Jihong Park, Kyeongtak Song, and Sae Yong Lee
Six Sessions of Anterior-to-Posterior Ankle Joint Mobilizations Improve Patient-Reported Outcomes in Patients With Chronic Ankle Instability: A Critically Appraised Topic
Erik A. Wikstrom, Sajad Bagherian, Nicole B. Cordero, and Kyeongtak Song
Clinical Scenario: Chronic ankle instability (CAI) is a complex musculoskeletal condition that results in sensorimotor and mechanical alterations. Manual therapies, such as ankle joint mobilizations, are known to improve clinician-oriented outcomes like dorsiflexion range of motion, but their impact on patient-reported outcomes remains less clear. Focused Clinical Question: Do anterior-to-posterior ankle joint mobilizations improve patient-reported outcomes in patients with chronic ankle instability? Summary of Key Findings: Three studies (2 randomized controlled trials and 1 prospective cohort) quantified the effect of at least 2 weeks of anterior-to-posterior ankle joint mobilizations on improving patient-reported outcomes immediately after the intervention and at a follow-up assessment. All 3 studies demonstrated significant improvements in at least 1 patient-reported outcome immediately after the intervention and at the follow-up assessment. Clinical Bottom Line: At least 2 weeks of ankle joint mobilization improves patient-reported outcomes in patients with chronic ankle instability, and these benefits are retained for at least a week following the termination of the intervention. Strength of Recommendation: Strength of recommendation is grade A due to consistent good-quality patient-oriented evidence.
Anterior-to-Posterior Ankle Joint Mobilizations Improve Dynamic Postural Control in Chronic Ankle Instability Patients: A Critically Appraised Topic
Erik A. Wikstrom, Sajad Bagherian, Gary Allen, and Kyeongtak Song
Clinical Scenario: Balance impairment is common in patients with chronic ankle instability (CAI), especially during dynamic tasks. Manual therapies, such as ankle joint mobilizations are known to improve clinician-oriented outcomes such as dorsiflexion range of motion, but their impact on sensorimotor outcomes such as dynamic postural control and the retention of benefits remains less clear. Focused Clinical Question: Do anterior-to-posterior ankle joint mobilizations improve dynamic postural control in patients with CAI relative to a control condition and are those benefits retained after termination of the treatment? Summary of Key Findings: Three studies quantified the immediate effect and two studies quantified the retained benefit of anterior-to-posterior ankle joint mobilizations on improving Star Excursion Balance Test (SEBT) reach distances. Two studies demonstrated large immediate improvements in SEBT reach distances and those same investigations found that those large improvements were retained. Clinical Bottom Line: Ankle joint mobilization appears to improve SEBT reach distances and those improvements are retained. Strength of Recommendation: Strength of recommendation is a B due to inconsistent moderate-quality patient-oriented evidence.
Joint Stabilization Surgery for Chronic Ankle Instability and Medial Ankle Osteoarthritis: A Critically Appraised Topic
Kyle B. Kosik, Kyeongtak Song, Phillip A. Gribble, Matthew C. Hoch, and Arjun Srinath
Clinical Scenario: Patients with chronic ankle instability (CAI) who require surgical intervention are often diagnosed with medial ankle osteoarthritis (OA). Lateral joint stabilization procedures are commonly performed among this patient population to restore bony alignment and improve cartilage loading patterns to increase patient-reported function and mitigate further degenerative changes. Focused Clinical Question: What is the available evidence to support joint stabilization procedures on patient-reported outcomes and progression of radiographic OA among patients with CAI who have medial ankle OA? Summary of Key Findings: An electronic search of relevant databases was performed to identify peer-reviewed articles examining preoperative and postoperative clinical outcomes and radiographic evidence of ankle OA. A total of 3 peer-reviewed articles were retrieved. All 3 articles employed a retrospective case series study design. All 3 articles demonstrated improved patient-reported outcomes at the final follow-up visit. Two articles demonstrated that between 11% and 27% of patients progressed in at least 1stage of radiographic ankle OA between the preoperative assessment and the final follow-up visit (40–56 mo). Clinical Bottom Line: Joint stabilization surgery for patients with CAI and medial ankle OA is associated with improved clinical outcomes and a low rate of worsening radiographic joint degeneration within the first 5 years. Strength of Recommendation: Consistent evidence exists across all 3 articles. However, this evidence is based on a low-quality study design. Therefore, there is a grade-C level of evidence to support joint stabilization for improving patient-reported and radiographic outcomes within the first 5 years after surgery for patients with CAI and medial ankle OA.
Altered Vertical Ground Reaction Force Components While Walking in Individuals With Chronic Ankle Instability
Erik A. Wikstrom, Kyeongtak Song, Kimmery Migel, and Chris J. Hass
Aberrant loading is a mechanism by which individuals with chronic ankle instability (CAI) may negatively impact cartilage health and therefore long-term health outcomes. We aimed to quantify walking vertical ground reaction force (vGRF) component differences between those with and without CAI. Participants (n = 36) walked barefoot overground at a self-selected comfortable pace. Normalized peak vGRF, time to peak vGRF, and normalized loading rate were calculated. Higher normalized loading rates (CAI: 5.69 ± 0.62 N/BW/s; controls: 5.30 ± 0.44 N/BW/s, p = .034) and less time to peak vGRF (CAI: 1.48 ± 0.18 s; controls: 1.62 ± 0.16 s, p = .018) were observed in those with CAI. In conclusion, those with CAI demonstrate a higher normalized loading rate and less time to peak vGRF compared to controls.
Reliability of Manually Segmenting T1ρ Magnetic Resonance Sequences of Talar Articular Cartilage
Kyeongtak Song, Kyle B. Kosik, Phillip A. Gribble, and Erik A. Wikstrom
Context: Quantifying early posttraumatic ankle osteoarthritis pathogenesis using compositional magnetic resonance (MR) imaging sequences is becoming more common. These MR sequences are often manually segmented to isolate the cartilage of interest before cartilage compositional values (eg, T1ρ or T2) are quantified. However, limited information is available regarding the reliability and reproducibility of manual segmentation for the entire talar dome. Objective: The purpose of this study was to determine the intraobserver and interobserver reliability of manually segmenting T1ρ MR sequences of the entire talar dome and 4 subregions of interest. Design: Descriptive observational study. Setting: Laboratory. Patients or Other Participants: Ten uninjured healthy individuals (4M and 6F: 21.40 [3.03] y, 170.00 [7.93] cm, 71.03 [14.97] kg) participated. Intervention: None. Main Outcome Measures: Two investigators manually segmented 10 T1ρ ankle MR sequences using ITK-SNAP software to calculate T1ρ mean relaxation times and cartilage volumes. Each observer repeated the segmentation twice, with segmentations separated by 1 month. Intraobserver and interobserver reliability was determined using intraclass correlation coefficients (ICCs) with 95% confidence intervals and root mean square coefficient of variations (RMSCVs). Results: For T1ρ relaxation time, intraobserver (ICC = .994–.997, RMSCV = 1.31%–1.51%) and interobserver reliability (ICC = .990, RMSCV = 2.36%) was excellent for the overall talar dome. Excellent intraobserver (ICC = .975–.980, RMSCV = 3.88%–4.59%) and excellent interobserver reliability (ICC = .970, RMSCV = 5.13%) was noted for overall talar cartilage volume. Conclusions: The results demonstrate that manual segmentation of the entire talar dome from a T1ρ MR is reliable and repeatable.
The Immediate Effects of Ankle Joint Mobilization on Ankle Musculotendinous Stiffness in Individuals With Chronic Ankle Instability
M. Spencer Cain, Kyeongtak Song, J. Troy Blackburn, Kimmery Migel, and Erik A. Wikstrom
Ankle joint mobilization has been shown to be effective at improving outcomes in those with chronic ankle instability (CAI), but the neuromuscular mechanisms are still unknown. We aimed to determine the immediate effect of a single Grade III anterior-to-posterior ankle joint mobilization bout on ankle musculotendinous stiffness (MTS) in those with CAI. Seventeen CAI participants had plantar flexor and fibularis MTS assessed before and after a 5-min joint mobilization treatment. MTS outcomes were estimated using the damped oscillation method. Fibularis (0.25 ± 0.41 N/m/kg, p = .028) but not plantar flexor MTS (−2.18 ± 14.35 N/m/kg, p = .539) changed following mobilization and exceeded the calculated minimal detectable change score (0.12 N/m/kg). Increased fibularis MTS may represent a neuromuscular mechanism by which ankle joint mobilizations improve postural control in those with CAI.
Impact of Plantar Massage and Ankle Mobilization on Visual Reliance in Those With Chronic Ankle Instability: A Randomized Controlled Trial
Erik A. Wikstrom, M. Spencer Cain, Kyeongtak Song, Brian Pietrosimone, J. Troy Blackburn, Jason R. Franz, Kimmery Migel, Jaeho Jang, and Feng-Chang Lin
Context: Those with chronic ankle instability (CAI) rely more on visual information to maintain postural control. Plantar massage and ankle joint mobilization are moderately successful at improving CAI-associated postural control impairments. Manual therapies may have a larger influence on the underlying sensory strategy used to maintain postural control, but their effect on these strategies remains unknown. Objective: To evaluate the effects of separate 2-week plantar massage and ankle joint mobilization interventions on estimates of visual reliance during single-limb stance in those with CAI and determine whether changes in visual reliance estimates were driven by concurrent changes in peripheral- or spinal-level sensorimotor function. Design: Randomized controlled clinical trial. Setting: Research laboratory. Patients: Sixty participants with CAI. Interventions: Participants were equally randomized into plantar massage, ankle joint mobilization, and control (no intervention) groups. The manual therapy groups received six 5-minute treatments of their respective interventions over a 2-week period. Main Outcome Measure: A percentage modulation outcome quantified an individual’s reliance on visual information by estimating the weight given to visual information during eyes-open stance based on the magnitude of postural instability that occurs with vision removed. Secondary measures included joint position sense, plantar light-touch thresholds, and the H-reflex. Outcomes were captured before (baseline), immediately after (post), and 1-month (follow-up) after the 2-week intervention. Results: Plantar massage resulted in significant percentage modulation changes in sagittal (P ≤ .046) but not frontal plane outcomes (P ≥ .069) relative to the control group. Joint mobilization did not alter percentage modulation changes (P ≥ .413). Significant correlations between percentage modulation changes and peripheral sensorimotor function were noted primarily at the 1-month follow-up. Conclusions: A 2-week plantar massage but not an ankle joint mobilization intervention alters sagittal plane percentage modulation values during single-limb stance in those with CAI. These changes may be driven by changes in peripheral sensorimotor function.
Real-Time External Focus of Attention Biofeedback During a Forward Hop-To-Stabilization on Dynamic Postural Stability in Individuals With Chronic Ankle Instability
Danielle M. Torp, Matthew C. Hoch, Kyle B. Kosik, Ke’La H. Porter, Stacey Slone, and Kyeongtak Song
Introduction: Chronic ankle instability (CAI) is a common sequela of lateral ankle sprains that impairs postural stability during functional tasks. External biofeedback may be an appropriate rehabilitation tool to improve functional movement; however, more research is needed to determine its effectiveness in dynamic tasks in individuals with CAI. This study aimed to assess the effect of real-time external biofeedback via laser on dynamic postural stability indices during a single-limb forward hop-to-stabilization task in participants with CAI. Methods: Eighteen participants with CAI completed five successful forward hop-to-stabilization jumps with and without external biofeedback using a single-dot laser attached to the distal tibia. A single inertial measurement unit fastened to the lower back captured dynamic postural stability indices in the vertical, anterior-posterior, medial-lateral, and the resultant of each plane during the 5 s after landing. The mean difference between biofeedback and no biofeedback was assessed using independent t tests. Results: Our results indicate no significant differences were observed between forward hop-to-stabilization tasks with and without real-time external biofeedback in individuals with CAI. Discussion: More research is needed to determine the appropriate biofeedback tool location and modality type of external biofeedback in addition to the minimum amount of training exposure to improve dynamic postural stability during a single-limb landing task.