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  • Author: Michael J. Ormsbee x
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Michael J. Ormsbee, Jeffrey A. Clapper, Joan L. Clapper and Matthew D. Vukovich

This study was designed to investigate the impact of dietary protein intake on serum concentrations of IGF-I and IGFBP-1 and relative amounts of serum IGFBP-3 during 6 d of physical activity. Ten men (23.8 ± 2.0 y of age) were assigned to 1 of 3 trials in a random crossover design. Each trial was isocaloric but with varying amounts of dietary protein: 50 g, 100 g, or 200 g. Subjects expended 500 kcal through treadmill running or weightlifting on alternate days for 6 d. Fasting blood samples were obtained for measurement of IGF-I, IGFBP-1, and IGFBP-3. Pre–post 24-h urine was measured for urea nitrogen. 50 g/d of protein resulted in a negative nitrogen balance, whereas 100 g/d and 200 g/d resulted in a positive nitrogen balance—200 g greater (P < 0.05) than 50 g and 100 g. Baseline IGF-I, BP-1, and BP-3 were not different among treatments. IGF-I decreased (P = 0.002) during the 6 d. Post intervention IGFBP-I was greater (P = 0.03) than at baseline. Post intervention IGFBP-3 values were not different from baseline or between trials. A 6-d modification of protein intake, while in energy balance, during a strength and conditioning program does not appear to modify serum concentrations of IGF-I or IGFBP-1 or relative amounts of IGFBP-3.

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Aaron P. Crombie, Pei-Yang Liu, Michael J. Ormsbee and Jasminka Z. Ilich


To examine relationships between changes in body weight, body composition, and fitness level in male students of the general population and those in the Army Reserve Officer Training Corps (ROTC) program during the freshman year of college.


Thirty-seven (18.4 ± 0.7 yr) healthy, nonsmoking, first-semesterresident male students were divided into 3 groups: low active (LA), high active (HA), and ROTC. Baseline (beginning of freshman year) and 6-month follow-up measurements included anthropometry, body composition (by DXA), 3-day food records, and physical activity (PA) assessment.


Weight and body-mass index did not change significantly within or among groups. HA participants compared with LA and ROTC had a significant decrease in body fat (–1.6% ± 2.5% vs. 1.9% ± 1.2% and 0.8% ± 2.2%, respectively). They also had a significant increase in lean mass compared with LA and ROTC (1.8 ± 1.1 kg vs. –0.2 ± 2.0 kg and 0.2 ± 1.7 kg, respectively). All p values were <.05. ROTC and LA participants were similar in all measures of body composition and PA and had significantly lower PA levels than the HA group. No significant relationships were observed between dietary variables and body-composition changes.


These results suggest that higher PA was the most powerful determinant in achieving favorable body-composition outcomes. In addition, current physical training conducted by ROTC at Florida State University (which seems to be a practice nationwide) might not be sufficient to offset gains in body fat.

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Paul J. Arciero, Christopher L. Gentile, Roger Martin-Pressman, Michael J. Ormsbee, Meghan Everett, Lauren Zwicky and Christine A. Steele

We investigated the effectiveness of two lifestyle modification programs of exercise training and nutritional intake (ad libitum) on improving body composition and disease risk in overweight/obese men and women. Sixty-three subjects were weight matched and assigned to one of three groups for a 12 wk intervention: 1) high-intensity resistance and cardiovascular training and a balanced diet (RC+BD, 40% CHO: 40% PRO; n = 27, 16 female/11 male, age = 42 ± 9 y); 2) moderate-intensity cardiovascular training and a traditional food guide pyramid diet (C+TD, CHO 50 to 55%; PRO 15 to 20%; FAT < 30%; n =19, 10 female/9 male, age = 43 ± 10 y); and 3) an inactive control group (C, n = 17, 5 female/12 male, age 43 ± 11 y). RC+BD resulted in more favorable changes (P < 0.01) in percent body fat (−15.8% vs. −6.9%) and abdominal fat (−15.6% vs. −7.5%) compared to C+TD and C. Total cholesterol (−13.8%), LDL-cholesterol (−20.8%), and systolic blood pressure (−5.7%) declined (P > 0.05) in RC+BD, whereas C+TD and C remained unchanged. Our results suggest that RC+BD may be more effective than C+TD and C in enhancing body composition and lowering cardiovascular risk in obese individuals.

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Michael J. Ormsbee, Brandon D. Willingham, Tasha Marchant, Teresa L. Binkley, Bonny L. Specker and Matthew D. Vukovich

We examined the effect of a protein supplement on muscular strength and body composition during 6 months of a 5 days/week concurrent strength and endurance training program. Sedentary males (n = 26) and females (n = 25), 18–25 years, were randomly assigned to receive a protein (PRO, 42 g/serving) or carbohydrate (CON) supplement twice daily. Strength and body composition (dual-energy X-ray absorptiometry) were assessed at baseline, 3 (3M), and 6 (6M) months. Protein intake was higher in PRO (PRO: 2.2 g/kg; CON: 1.1 g/kg; p < .001). Females in both groups gained similar strength at 3M and 6M in bench press and hip sled. Males in PRO gained more bench press strength at 3M (PRO: 24.6 ± 3.2 kg; CON: 14.3 ± 3.8 kg; p = .06) and 6M (PRO: 34.4 ± 4.3 kg; CON: 18.7 ± 5.1 kg; p = .03) and hip sled strength at 3M (PRO: 67.7 ± 9.2 kg; CON: 40.8 ± 10.8 kg, p = .07) and 6M (PRO: 94.0 ± 10.6 kg; CON: 65.1 ± 12.4 kg; p = .09) compared with CON. Females in PRO experienced a greater reduction in fat mass over the course of the study (6M) than CON (PRO: −1.7 ± 0.5 kg; CON: 0.1 ± 0.5 kg; p = .06). Changes in lean mass were similar for females in PRO and CON. Loss in fat mass was similar for males in PRO and CON at 3M and 6M. Males in PRO gained more lean mass at 3M compared with CON (PRO: 3.2 ± 0.3 kg; CON: 2.2 ± 0.4 kg; p = .1) but similar gains at 6M (PRO: 2.6 ± 0.4 kg; CON: 2.2 ± 0.5 kg; p = .6). The results of this study demonstrate that PRO used during a concurrent training program may augment positive changes in body composition in young sedentary males and females, and strength gains in males.