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Compared with mainstream sport athletes, relatively little is known regarding the factors affecting the development of athletes with a disability. Sport-specific training programs are essential to athletes’ successful performance; to create appropriate programs and strategies, a clear understanding of the nuances of development of athletes with a disability is important. The objective of this systematic review was to synthesize existing research on development in athletes with a disability and examine the key determinants of successful development and sporting performance. After a search of the Web of Science and SPORTDiscus databases, 21 articles were identified that met the inclusion criteria, which were assessed using the Mixed Methods Appraisal Tool and categorized into 3 groups: training and practice, shortterm interventions, and long-term changes due to training. Among the studies, there was a disproportionate focus on immediate interventions and training programs and less on long-term development. The review reflected a lack of research on sportspecific development of athletes with a disability, which raises concerns regarding the effectiveness and appropriateness of current training practices.