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Jeffrey J. Zachwieja, David L. Costill and William J. Fink

To determine the effect of carbohydrate feeding on muscle glycogen resynthesis, 8 male cyclists pedaled for 2 hrs on a cycle ergometer at 70% of VO2max while consuming either a 10% carbohydrate solution (CHO) or a nonnutritive sweet placebo (No CHO). Muscle biopsies were obtained from the vastus lateralis prior to, immediately postexercise, and at 2,4, and 24 hrs of recovery. Blood samples were taken before and at the end of exercise, and at specified times during recovery. During both trials food intake was withheld for the first 2 hrs of recovery, but at 2 hrs postexercise a 24% carbohydrate solution was ingested. The rate of muscle glycogen resynthesis during the first 2 hrs of recovery was similar for the CHO and No CHO trials. Following ingestion of the 24% carbohydrate supplement, the rates of muscle glycogen resynthesis increased similarly in both trials. These similar rates of resynthesis following ingestion of the carbohydrate supplement were obtained despite significantly greater serum glucose and insulin levels during the No CHO trial. The results indicate that the carbohydrate feedings taken during exercise had little effect on postexercise muscle glycogen resynthesis.

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Christopher Barnett, David L. Costill, Mathew D. Vukovich, Kevin J. Cole, Bret H. Goodpaster, Scott W. Trappe and William J. Fink

This study examined the effects of 14 days of L-camitine supplementation on muscle and blood camitine fractions, and muscle and blood lactate concentrations, during high-intensity sprint cycling exercise. Eight subjects performed three experimental trials: control 1 (CON I, Day 0), control I! (CON II, Day 14), and L-camitine (L-CN, Day 28). Each trial consisted of a 4-rain ride at 90% VO2max, followed by a rest period of 20 min, and thee five repeated 1-min rides at 115% VO2max (2 min rest between each). Following CON n, all subjects began dietary supplementation of L-camitine for a period of 14 days (4 g/day). Plasma total acid soluble and free camitine concentrations were significantly higher (p < .05) at all time points following supplementation. L-camitine supplementation had no significant effect on muscle camitine content and thus could not alter lactate accumulation during exercise.

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Kevin J. Cole, David L. Costill, Raymond D. Starling, Bret H. Goodpaster, Scott W. Trappe and William J. Fink

The purpose of this investigation was to determine the effect of caffeine ingestion on work output at various levels of perceived exertion during 30 min of isokinetie variable-resistance cycling exercise. Ten subjects completed six trials 1 hr after consuming either 6 mg · kg−1 caffeine (3 trials) or a placebo (3 trials). During each trial the subjects cycled at what they perceived to be a rating of 9 on the Borg rating of perceived exertion scale for the first 10 min, a rating of 12 for the next 10 min, and a rating of 15 for the final 10 min. Total work performed during the caffeine trials averaged 277.8 ± 26.1 kJ, whereas the mean total work during the placebo trials was 246.7 ± 21.5 kJ (p < .05). Blood glycerol and free fatty acid levels increased over time to a significantly greater degree in the caffeine trials than in the placebo trials (p < .05). However, there were no significant differences between conditions in respiratory exchange ratio. These data suggest that caffeine may play an ergogenic role in exercise performance by altering both neural perception of effort and substrate availability.