The present study explored the relationships among gratitude, sport satisfaction, athlete burnout, and perceived social support among college student-athletes in the United States. Participants (N = 293) from 16 different types of sports at 8 NCAA Division I and III institutions were surveyed. Results indicated gratitude was negatively correlated with burnout and positively correlated with sport satisfaction, suggesting that athletes who reported more general gratitude also experienced lower levels of burnout and greater levels of satisfaction with their college sport experience. Perceived social support was found to be a mediator in both relationships. Limitations and implications for research and practice are discussed.