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Gender- and Puberty-Dependent Association Between Physical Activity and Depressive Symptoms: National Survey Among Chinese Adolescents

Ying Sun, Jing An, Xi Wang, Ping Zu, and Fang-Biao Tao

Background:

The study aims to understand the possible gender difference in the associations between physical activity and depressive symptoms during pubertal transition.

Methods:

Participants were 30,399 children and adolescents of Han ethnicity from urban and rural areas in 8 cities in China. Physical activity (PA) and depressive symptom was assessed by adapted Youth Risk Behavior Survey and Children Depression Inventory (CDI), respectively. Pubertal development was assessed by trained physicians.

Results:

In China, over 30% boys and 40% girls reported having no vigorous PA (VPA) or moderate PA (MPA) in the past week. In girls, participating in VPA 1 to 2 days/week showed protective effect for depressive symptoms; whereas in boys, participating in MPA 1 to 2 days/week showed protective effect for depressive symptoms at and after genital stage III (G3).

Conclusions:

Moderate frequency (1 to 2 days/week) in PA undertaken might be encouraged to prevent depressive symptoms among adolescents.

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Electroacupuncture-Enhanced Differentiation of Bone Marrow Stromal Cells into Neuronal Cells

Zhongren Sun, Xiaoning Li, Zhiqiang Su, Ying Zhao, Li Zhang, and Mingyuan Wu

Context:

Bone marrow stromal cells (BMSCs) can be differentiated into neuronal cells and are used to treat spinal cord injury (SCI).

Objective:

This study investigated whether electroacupuncture enhances BMSC’s effects on SCI in rats.

Design:

The effects of transplantation of phosphate-buffered saline or BMSC, electroacupuncture, and a combination of BMSC transplantation and electroacupuncture on SCI were evaluated using a combined behavioral score (CBS). Expressions of neuronal marker neuron-specific enolase (NSE) and gliocyte-specific marker glial fibrillary acidic protein (GFAP) of transplanted BMSC were detected using immunohistochemistry to assess the effect of electroacupuncture on differentiation of BMSC into neuronal cells.

Results:

The combination of BMSC transplantation and electroacupuncture significantly alleviated CBS in rats with SCI compared with the separate treatment of BMSC or electroacupuncture. In addition, electroacupuncture increased the NSE- and GFAP-positive transplanted BMSCs in spinal cord.

Conclusion:

Combined treatment showed a better effect, and the mechanisms may be partially caused by enhanced differentiation of BMSC into neuronal cells. Future studies are needed to confirm this.